Mutation glpK22(fbR)
- Name: glpK22(fbR)
- Type: Base Pair Substitution
- Mutation of Gene: glpK
- Approx. Map Location: 88.66
- Properties
Property Symbol feedback resistant fbR - Comments
- This allele is both Ki (insensitive to inhibition by fructose bisphosphate) and Kr (resistant to inhibition by IIAglu of the PTS) . Sequenced allele: G304S.
- References
- Pettigrew, D.W., W.Z. Liu, C. Holmes, N.D. Meadow, S. Roseman 1996. A single amino acid change in Escherichia coli glycerol kinase abolishes glucose control of glycerol utilization in vivo. J.Bacteriol. 178:2846-2852
- Holtman, C.K., A.C. Pawlyk, N.D. Meadow, D.W. Pettigrew 2001. Reverse genetics of Escherichia coli glycerol kinase allosteric regulation and glucose control of glycerol utilization in vivo. J.Bacteriol. 183:3336-3344
- 3 Strains Carrying This Mutation
Name Mutations Genotype Lin 43 11 Hfr(PO2A), fhuA22, ΔphoA8, fadL701(T2R), relA1, glpR2(glpc), pitA10, spoT1, glpK22(fbR), rrnB-2, mcrB1, creC510 Lin 297 12 Hfr(PO2A), fhuA22, ΔphoA8, fadL701(T2R), relA1, glpR2(glpc), pitA10, spoT1, glpK22(fbR), rrnB-2, mcrB1, creC510, mgr-7(mgr) Lin 298 12 Hfr(PO2A), fhuA22, ΔphoA8, fadL701(T2R), relA1, glpR2(glpc), pitA10, spoT1, glpK22(fbR), rrnB-2, mcrB1, creC510, mgr-8