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Product dihydrofolate reductase
| dihydrofolate reductase |
| DHFR |
| Host Site | Page Links |
|---|---|
| EcoCyc | DIHYDROFOLATEREDUCT-MONOMER |
In Klebsiella, appears to be a negative regulator of arylsufatase synthesis (Azakami et al. J.Bacteriol. 174:2344 (1992))
- Ohmae, E., K. Iriyama, S. Ichihara, K. Gekko 1996. Effects of point mutations at the flexible loop glycine-67 of Escherichia coli dihydrofolate reductase on its stability and function. J.Biochem.(Tokyo) 119:703-710
- Cummins, PL, JE Gready 2001. Energetically most likely substrate and active-site protonation sites and pathways in the catalytic mechanism of dihydrofolate reductase. J. Am. Chem. Soc. 123(15):3418-28.