Product UDP-N-acetylmuramoyl-pentapeptide:undecaprenyl-PO4 phospho-N-acetylmuramoyl-pentapeptide transferase
UDP-N-acetylmuramoyl-pentapeptide:undecaprenyl-PO4 phospho-N-acetylmuramoyl-pentapeptide transferase |
phospho-N-acetylmuramoyl pentapeptide transferase |
Host Site | Page Links |
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EcoCyc | PHOSNACMURPENTATRANS-MONOMER |
first step in lipid cycle rxs. in biosynthesis of bacterial cell wall. inhibited by tunicamycin and liposidomycin B and mureidomycin A
- Ikeda, M., M. Wachi, H.K. Jung, F. Ishino, M. Matsuhashi 1991. The Escherichia coli mraY gene encoding UDP-N-acetylmuramoyl-pentapeptide: undecaprenyl-phosphate phospho-N-acetylmuramoyl-pentapeptide transferase. J.Bacteriol. 173:1021-1026
- Brandish, P.E., K.I. Kimura, M. Inukai, R. Southgate, J.T. Lonsdale, T.D. Bugg 1996. Modes of action of tunicamycin, liposidomycin B, and mureidomycin A: inhibition of phospho-N-acetylmuramyl-pentapeptide translocase from Escherichia coli. Antimicrob.A