Site acnA
- Name: acnA
- Type: Gene
- Synonyms
b1276 MG1655 locus tag - Mnemonic: aconitase
- Left End Point: 28.75
- Right End Point: 28.81
- Products:
aconitase citrate (isocitrate) lyase - Direction: >
- Priority: 0
- 1 Alleles of This Gene
acnA785(del)::kan - External Database Links:
Host Site Page Links NCBI/GenBank X60293 EcoGene.org EG11325 EcoliWiki acnA - Comment:
- NEW, post'90.length 2.67 kb. 890 codons sans start & stop. see ref. sugg. enzy may also have fe-responsive fctn, and euk. fe-responsive prot. may be a cytoplasmic aconitase. + regulated by Fur.
- References:
- Prodromou, C., M.J. Haynes, J.R. Guest 1991. The aconitase of Escherichia coli: purification of the enzyme and molecular cloning and map location of the gene (acn). J.Gen.Microbiol. 137:2505-2515
- Prodromou, C., P.J. Artymiuk, J.R. Guest 1992. The aconitase of Escherichia coli: nucleotide sequence of the aconitase gene and amino acid sequence similarity with mitochondrial aconitases, the iron-responsive-element-binding protein and isopropylmalat
- Cunningham, L., M.J. Gruer, J.R. Guest 1997. Transcriptional regulation of the aconitase genes (acnA and acnB) of Escherichia coli. Microbiology 143:3795-3805
- Fuentes, A.M., J.J. Diaz-Mejia, R. Maldonado-Rodriguez, C.F. Amabile-Cuevas 2001. Differential activities of the SoxR protein of Escherichia coli: SoxS is not required for gene activation under iron deprivation. FEMS Microbiol.Lett. 201:271-275
- Schaller, A, M Guo, O Gisanrin, Y Zhang 2002. Escherichia coli genes involved in resistance to pyrazinoic acid, the active component of the tuberculosis drug pyrazinamide. FEMS Microbiol. Lett. 211(2):265-70.
- Masse, E., S. Gottesman 2002. A small RNA regulates the expression of genes involved in iron metabolism in Escherichia coli. Proc.Natl.Acad.Sci.USA 99:4620-4625