Site murI
- Name: murI
- Type: Gene
- Synonyms
b3967 MG1655 locus tag dga Dougherty et al. glr Yoshimura et al. - Mnemonic: Murein
- Left End Point: 89.74
- Right End Point: 89.75
- Products:
glutamate racemase - Direction: >
- Priority: 0
- 1 Alleles of This Gene
murI796-YFP(::cat) - External Database Links:
Host Site Page Links EcoGene.org EG11204 EcoliWiki murI - Comment:
- Check on Name precedence. dga v. murI vs. glr. To construct D-glutamate auxotrophs, must transfer gltS (transport) mutation, then murI mutation.
- References:
- Brosius, J., T.J. Dull, D.D. Sleeter, H.F. Noller 1981. Gene organization and primary structure of a ribosomal RNA operon from Escherichia coli. J.Mol.Biol. 148:107-127
- Doublet, P., J. van Heijenoort, D. Mengin-Lecreulx 1992. Identification of the Escherichia coli murI gene, which is required for the biosynthesis of D-glutamic acid, a specific component of bacterial peptidoglycan. J.Bacteriol. 174:5772-5779
- Baliko, G., P. Venetianer 1993. An Escherichia coli gene in search of a function: phenotypic effects of the gene recently identified as murI. J.Bacteriol. 175:6571-6577
- Yoshimura, M., M. Ashiuchi, N. Esaki, C. Kobatake, S.-Y. Choi, K. Soda 1993. Expression of glr (murI, dga) gene encoding glutamate racemase in Escherichia coli. J.Biol.Chem. 268:24242-24246
- Dougherty, T.J., J.A. Thanassi, M.J. Pucci 1993. The Escherichia coli mutant requiring D-glutamic aid is the result of mutations in two distinct genetic loci. J.Bacteriol. 175:111-116
- Doublet, P., J. van Heijenoort, J.P. Bohin, D. Mengin-Lecreulx 1993. The murI gene of Escherichia coli is an essential gene that encodes a glutamate racemase activity. J.Bacteriol. 175:2970-2979
- Liu, L., T. Yoshimura, K. Endo, K. Kishimoto, Y. Fuchikami, J.M. Manning, N. Esaki, K. Soda 1998. Compensation for D-glutamate auxotrophy of Escherichia coli WM335 by D-amino acid aminotransferase gene and regulation of murI expression. Biosci. Biotech