Site recC
- Name: recC
- Type: Gene
- Synonyms
b2822 MG1655 locus tag - Mnemonic: Recombination
- Left End Point: 63.74
- Right End Point: 63.81
- Products:
exonuclease V subunit RecBCD enzyme subunit exonuclease V subunit exonuclease/helicase - Direction: <
- Priority: 1
- 9 Alleles of This Gene
recC1001(Chi-) recC1002(Chi-) recC1003(Chi-) recC1004(Chi-) recC1010(Nuc-) recC22 recC23 recC73 recC747(del)::kan - External Database Links:
Host Site Page Links NCBI/GenBank X03966 EcoGene.org EG10825 EcoliWiki recC - Comment:
- muts are def. for homol.recomb., sens. to DNA-damaging agents and unable to restrict foreign DNA and produce inviable cells in culture. RecBCD req. for MMS repair,not recomb.or UV or mitomycin repair
- References:
- Hickson, I.D., P.T. Emmerson 1981. Identification of the Escherichia coli recB and recC gene products. Nature 294:578-580
- Sasaki, M., T. Fujiyoshi, K. Shimada, Y. Takagi 1982. Fine structure of the recB and recC gene region of Escherichia coli. Biochem.Biophys.Res.Commun. 109:414-422
- Fleming, T.P., M.S. Nahlik, M.A. McIntosh 1983. Regulation of enterobactin iron transport in Escherichia coli: characterization of ent::Mu d(Ap^r lac) operon fusions. J.Bacteriol. 156:1171-1177
- Dykstra, C.C., D. Prasher, S.R. Kushner 1984. Physical and biochemical analysis of the cloned recB and recC genes of Escherichia coli K-12. J.Bacteriol. 157:21-27
- Chaudhury, A.M., G.R. Smith 1985. Role of Escherichia coli RecBC enzyme in SOS induction. Mol.Gen.Genet. 201:525-528
- Finch, P.W., R.E. Wilson, K. Brown, I.D. Hickson, A.E. Tomlinson, P.T. Emmerson 1986. Complete nucleotide sequence of the Escherichia coli recC gene and of the thyA-recC intergenic region. Nucleic Acids Res. 14:4437-4451
- Clark, A.J. 1991. rec genes and homologous recombination proteins in Escherichia coli. Biochimie 73:523-532
- Taylor, A.F., G.R. Smith 1995. Strand specificity of nicking of DNA at Chi sites by RecBCD enzyme. Modulation by ATP and magnesium levels. J.Biol.Chem. 270:24459-24467
- Taylor, A.F., G.R. Smith 1995. Monomeric RecBCD enzyme binds and unwinds DNA. J.Biol.Chem. 270:24451-24458
- Poteete, A.R., A.C. Fenton 2000. Genetic requirements of phage lambda red-mediated gene replacement in Escherichia coli K-12. J.Bacteriol. 182:2336-2340