Site clpA
- Name: clpA
- Type: Gene
- Synonyms
b0882 MG1655 locus tag - Mnemonic: caseinolytic protease
- Left End Point: 19.89
- Right End Point: 19.93
- Products:
Clp ATP-dependent protease, ATP-binding subu. - Direction: >
- Properties:
Property Comment encodes a protease NULL regulatory gene NULL - Priority: 0
- 3 Alleles of This Gene
clpA319::mini-kan clpA783(del)::kan clpA791-YFP(::cat) - External Database Links:
Host Site Page Links EcoGene.org EG10156 EcoliWiki clpA - Comment:
- References:
- Gottesman, S., W.P. Clark, M.R. Maurizi 1990. The ATP-dependent Clp-protease of Escherichia coli. Sequence of clpA and identification of a Clp-specific substrate. J.Biol.Chem. 265:7886-7893
- Tobias, J.W., T.E. Shrader, G. Rocap, A. Varshavsky 1991. The N-end rule in bacteria. Science 254:1374-1377
- Shrader, T.E., J.W. Tobias, A. Varshavsky 1993. The N-end rule in Escherichia coli: cloning and analysis of the leucyl, phenylalanyl-tRNA-protein transferase gene aat. J.Bacteriol. 175:4364-4374
- Shapiro, J.A. 1993. A role for the Clp protease in activating Mu-mediated DNA rearrangements. J.Bacteriol. 175:2625-2626
- Seol, J.H., K.M. Woo, M.S. Kang, D.B. Ha, C.H. Chung 1995. Requirement of ATP hydrolysis for assembly of ClpA/ClpP complex, the ATP-dependent protease Ti in Escherichia coli. Biochem.Biophys.Res.Commun. 217:41-51
- Seol, J.H., J.A. Kwon, S.J. Yoo, H.S. Kim, M.S. Kang, C.H. Chung 1997. Site-directed mutagenesis of the Cys residues in ClpA, the ATPase component of protease Ti (ClpAP) in Escherichia coli. Biol. Chem 378:1205-1209