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Site rusA(qsr')
- Name: rusA(qsr')
- Type: Gene
- Synonyms
b0550 MG1655 locus tag rus rusA - Mnemonic: ruv suppressor
- Left End Point: 12.34
- Right End Point: 12.35
- Products:
resolvase (endonuclease) in qsr' - Direction: >
- Properties:
Property Comment cryptic prophage element NULL - Priority: 0
- 1 Alleles of This Gene
rusA(qsr')-3(del)::kan - External Database Links:
Host Site Page Links EcoGene.org EG20283 EcoliWiki rusA(qsr') - Comment:
- An endonuclease that can resolve Holliday intermediates. Corrects RuvAB- or RuvC- defects in recombination and repair.
- References:
- Mandal, T.N., A.A. Mahdi, G.J. Sharples, R.G. Lloyd 1993. Resolution of Holliday intermediates in recombination and DNA repair: indirect suppression of ruvA, ruvB, and ruvC mutations. J.Bacteriol. 175:4325-4334
- Sharples, G.J., S.N. Chan, A.A. Mahdi, M.C. Whitby, R.G. Lloyd 1994. Processing of intermediates in recombination and DNA repair identification of a new endonuclease that specifically cleaves Holliday junctions. EMBO J. 13:6133-6142
- Mahdi, A.A., G.J. Sharples, T.N. Mandal, R.G. Lloyd 1996. Holliday junction resolvases encoded by homologous rusA genes in Escherichia coli K-12 and phage 82. J.Mol.Biol. 257:561-573
- Chan, S.N., S.D. Vincent, R.G. Lloyd 1998. Recognition and manipulation of branched DNA by the RusA Holliday junction resolvase of Escherichia coli. Nucleic Acids Res. 26:1560-1566