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Site def
- Name: def
- Type: Gene
- Synonyms
b3287 MG1655 locus tag fms Meinnel and Blanquet, 1993 - Mnemonic: deformylase
- Left End Point: 73.96
- Right End Point: 73.97
- Products:
peptide deformylase N-formylmethionylaminoacyl-tRNA deformylase - Direction: >
- Priority: 0
- 1 Alleles of This Gene
def-791-YFP(::cat) - External Database Links:
Host Site Page Links EcoGene.org EG11440 EcoliWiki def - Comment:
- References:
- Meinnel, T., S. Blanquet 1993. Evidence that peptide deformylase and methionyl-tRNA(fMet) formyltransferase are encoded within the same operon in Escherichia coli. J.Bacteriol. 175:7737-7740
- Mazel, D., S. Pochet, P. Marliere 1994. Genetic characterization of polypeptide deformylase, a distinctive enzyme of eubacterial translation. EMBO J. 13:914-923
- Meinnel, T., S. Blanquet 1995. Enzymatic properties of Escherichia coli peptide deformylase. J.Bacteriol. 177:1883-1887
- Meinnel, T., C. Lazennec, S. Blanquet 1995. Mapping of the active site zinc ligands of peptide deformylase. J.Mol.Biol. 254:175-183
- Meinnel, T., S. Blanquet, F. Dardel 1996. A new subclass of the zinc metalloproteases superfamily revealed by the solution structure of peptide deformylase. J.Mol.Biol. 262:375-386
- Rajagopalan, P.T., A. Datta, D. Pei 1997. Purification, characterization, and inhibition of peptide deformylase from Escherichia coli. Biochemistry 36:13910-13918
- Green, B.G., J.H. Toney, J.W. Kozarich, S.K. Grant 2000. Inhibition of bacterial peptide deformylase by biaryl acid analogs. Arch.Biochem.Biophys. 375:355-358