Site rfaK
- Name: rfaK
- Type: Gene
- Synonyms
b3623 MG1655 locus tag waaK waaU Heinrichs et al. 1999 - Mnemonic: Rough
- Left End Point: 81.82
- Right End Point: 81.84
- Products:
RfaK transferase - Direction: <
- Properties:
Property Comment NOT similar to Not similar to RfaK of Salmonella and E. coli LPS core type R2 (which is an LPS N-acetylglucosaminyl transferase) in either sequence or nature of modification. - Priority: 0
- External Database Links:
Host Site Page Links EcoGene.org EG11423 EcoliWiki rfaK - Comment:
- RfaK: Modif.of the LPS core--essential for addition of O antigen to core. Not similar to RfaK in Salm. and coli LPS core type R2 (see above) in either sequence or nature of modification.
- References:
- Schnaitman, C.A., C. Parker, J.D. Klena, E. Pradel, N.B. Pearson, K.E. Sanderson, P.R. MacLachlan 1991. Physical maps of the rfa loci of Escherichia coli K-12 and Salmonella typhimurium. J.Bacteriol. 173:7410-7411
- Klena, J.D., R.S. Ashford, C.A. Schnaitman 1992. Role of Escherichia coli K-12 rfa genes and the rfp gene of Shigella dysenteriae 1 in generation of lipopolysaccharide core heterogeneity and attachment of O antigen. J.Bacteriol. 174:7297-7307
- Roncero, C., M.J. Casadaban 1992. Genetic analysis of the genes involved in synthesis of the lipopolysaccharide core in Escherichia coli K-12. J.Bacteriol. 174:3250-3260
- Klena, J.D., E. Pradel, C.A. Schnaitman 1992. Comparison of lipopolysaccharide biosynthesis genes rfaK, rfaL, rfaY, and rfaZ of Escherichia coli K-12 and Salmonella typhimurium. J.Bacteriol. 174:4746-4752
- Schnaitman, CA, JD Klena 1993. Genetics of lipopolysaccharide biosynthesis in enteric bacteria. Microbiol. Rev. 57(3):655-82.
- Sofia, H.J., V.D. Burland, D.L. Daniels, G. Plunkett, F.R. Blattner 1994. Analysis of the Escherichia coli genome. V. DNA sequence of the region from 76.0 to 81.5 minutes. Nucleic Acids Res. 22:2576-2586
- Heinrichs, D.E., M.A. Monteiro, M.B. Perry, C. Whitfield 1998. The assembly system for the lipopolysaccharide R2 core-type of Escherichia coli is a hybrid of those found in Escherichia coli K-12 and Salmonella enterica. Structure and function of the R2