Site pheS
- Name: pheS
- Type: Gene
- Synonyms
b1714 MG1655 locus tag fitA e.g.,Munavar and Jayaraman for fitA76 phe-act - Mnemonic: Phenylalanine
- Left End Point: 38.71
- Right End Point: 38.73
- Products:
phenylalanyl-tRNA synthetase alpha subunit - Direction: <
- Priority: 1
- 2 Alleles of This Gene
pheS11 pheS5(ts) - External Database Links:
Host Site Page Links EcoGene.org EG10709 EcoliWiki pheS - Comment:
- Selectable phenotype. Fluorophenylalanine resistance. Temperature-conditional loss, in thyA-: resistance to thymineless death.
- References:
- Fangman, W.L., F.C. Neidhardt 1964. Demonstration of an altered aminoacyl ribonucleic acid synthetase in a mutant of Escherichia coli. J.Biol.Chem. 239:1839-1843
- Kaplan, S., D. Anderson 1968. Selection of temperature-sensitive activating enzyme mutants in Escherichia coli. J.Bacteriol. 95:991-997
- Plumbridge, J.A., M. Springer 1980. Genes for the two subunits of phenylalanyl-tRNA synthetase of Escherichia coli are transcribed from the same promoter. J.Mol.Biol. 144:595-600
- Plumbridge, J.A., M. Springer, M. Graffe, R. Goursot, M. Grunberg-Manago 1980. Physical localisation and cloning of the structural gene for E. coli initiation factor IF3 from a group of genes concerned with translation. Gene 11:33-42
- Elseviers, D., P. Gallagher, A. Hoffman, B. Weinberg, I. Schwartz 1982. Molecular cloning and regulation of expression of the genes for initiation factor 3 and two aminoacyl-tRNA synthetases. J.Bacteriol. 152:357-362
- Plumbridge, J.A., M. Springer 1982. Escherichia coli phenylalanyl-tRNA synthetase operon: transcription studies of wild-type mutated operons on multicopy plasmids. J.Bacteriol. 152:661-668
- Springer, M., J.A. Plumbridge, M. Trudel, M. Graffe, M. Grunberg-Manago 1982. Transcription units around the gene for E. coli translation initiation factor IF3 (infC). Mol.Gen.Genet. 186:247-252
- Springer, M., M. Trudel, M. Graffe, J.A. Plumbridge, G. Fayat, J.-F. Mayaux, C. Sacerdot, S. Blanquet, M. Grunberg-Manago 1983. Escherichia coli phenylalanyl-tRNA synthetase operon is controlled by attenuation in vivo. J.Mol.Biol. 171:263-279
- Fayat, G., J.-F. Mayaux, C. Sacerdot, M. Fromant, M. Springer, M. Grunberg-Manago, S. Blanquet 1983. Escherichia coli phenylalanyl-tRNA synthetase operon region: evidence for an attenuation mechanism. Identification of the gene for the ribosomal prote
- Wu, T.-H., D.L. Wood, P.L. Stein, M.M. Comer 1984. Transcription of a gene cluster coding for two aminoacyl-tRNA synthetases and an initiation factor in Escherichia coli. J.Mol.Biol. 173:177-209
- Springer, M., J.-F. Mayaux, G. Fayat, J.A. Plumbridge, M. Graffe, S. Blanquet, M. Grunberg-Manago 1985. Attenuation control of the Escherichia coli phenylalanyl-tRNA synthetase operon. J.Mol.Biol. 181:467-478
- Mechulam, Y., G. Fayat, S. Blanquet 1985. Sequence of the E. coli pheST operon and identification of the himA gene. J.Bacteriol. 163:787-791
- Mechulam, Y., S. Blanquet, G. Fayat 1987. Dual level control of the Escherichia coli pheST-himA operon expression. tRNA$^{Phe}$-dependent attenuation and transcriptional operator-repressor control by himA and the SOS network. J.Mol.Biol. 197:453-470
- Munavar, M.H., R. Jayaraman 1993. Genetic evidence for interaction between fitA, fitB and rpoB gene products and its implication in transcription control in Escherichia coli. J.Genet. 72:21-23
- Vidya, S., B.P. Kamalakar, M.H. Munavar, L.S. Kumar, R. Jayaraman 2006. Allele-specific suppression of the temperature sensitivity of fitA/fitB mutants of Escherichia coli by a new mutation (fitC4): isolation, characterization and its implications in t