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Site ftsI
- Name: ftsI
- Type: Gene
- Synonyms
b0084 MG1655 locus tag pbpB penicillin binding protein 1983 map sep - Mnemonic: filamentation temperature sensitivity
- Left End Point: 1.97
- Right End Point: 2.01
- Products:
peptidoglycan synthetase; penicillin-binding protein 3 septum peptidoglycan synthetase PBP 3 - Direction: >
- Priority: 1
- 2 Alleles of This Gene
ftsI2158(ts) ftsI23(ts) - External Database Links:
Host Site Page Links EcoGene.org EG10341 EcoliWiki ftsI - Comment:
- periplasmic domain is involved in peptidoglycan synthesis; Has sm.N-term,cytopl.domain, memb.-spanning dom.and lge.periplasmic.Involved in septum formation;low-copy number, part of septosomal complex
- References:
- Nakamura, H., M. Maruyama, M. Soma, J.-I. Kato, H. Suzuki, Y. Hirota 1983. On the process of cellular division in Escherichia coli: nucleotide sequence of the gene for penicillin-binding protein. Mol.Gen.Genet. 191:1-9
- Begg, K.J., W.D. Donachie 1985. Cell shape and division in Escherichia coli: experiments with shape and division mutants. J.Bacteriol. 163:615-622
- Jung, H.K., F. Ishino, M. Matsuhashi 1989. Inhibition of growth of ftsQ, ftsA, and ftsZ mutant cells of Escherichia coli by amplification of a chromosomal region encompassing closely aligned cell division and cell growth genes. J.Bacteriol. 171:6379-63
- Mengin-Lecreulx, D., C. Parquet, L.R. Desviat, J. Pla, B. Flouret, J.A. Ayala 1989. Organization of the murE-murG region of Escherichia coli: identification of the murD gene encoding the D-glutamic-acid-adding enzyme. J.Bacteriol. 171:6126-6134
- Goffin, C., C. Fraipont, J. Ayala, M. Terrak, M. Nguyen-Disteche, J.M. Ghuysen 1996. The non-penicillin-binding module of the tripartite penicillin-binding protein 3 of Escherichia coli is required for folding and/or stability of the penicillin-binding
- Hara, H., S. Yasuda, K. Horiuchi, J.T. Park 1997. A promoter for the first nine genes of the Escherichia coli mra cluster of cell division and cell envelope biosynthesis genes, including ftsI and ftsW. J.Bacteriol. 179:5802-5811
- Huls, P.G., N.O. Vischer, C.L. Woldringh 1999. Delayed nucleoid segregation in Escherichia coli. Mol.Microbiol. 33:959-970
- Hale, C.A., P.A. de Boer 2002. ZipA is required for recruitment of FtsK, FtsQ, FtsL, and FtsN to the septal ring in Escherichia coli. J.Bacteriol. 184:2552-2556
- Piette, A., C. Fraipont, T. Den Blaauwen, M.E. Aarsman, S. Pastoret, M. Nguyen-Disteche 2004. Structural determinants required to target penicillin-binding protein 3 to the septum of Escherichia coli. J.Bacteriol. 186:6110-6117