Site pabB
- Name: pabB
- Type: Gene
- Synonyms
b1812 MG1655 locus tag - Mnemonic: para-Aminobenzoate
- Left End Point: 40.80
- Right End Point: 40.83
- Products:
aminodeoxychorismate (ADC) synthase subunit - Direction: >
- Priority: 1
- 4 Alleles of This Gene
pabB3 pabB5 pabB7(del)::kan pabB736(del)::kan - External Database Links:
Host Site Page Links NCBI/GenBank K02673 EcoGene.org EG10683 EcoliWiki pabB - Comment:
- Selectable phenotype. Constitutive: sulfonamide resistance. 40%,45% nuc.homol. with trpE and entC, other chor. binding prot.; also prot. seq. simil. paba biosynthesis
- References:
- Goncharoff, P., B. Nichols 1984. Nucleotide sequence of Escherichia coli pabB indicates a common evolutionary origin of p-aminobenzoate synthetase and anthranilate synthetase. J.Bacteriol. 159:57-62
- Bruce, I., J. Hardy, K.A. Stacey 1984. Potentiation by purines of the growth-inhibitory effects of sulphonamides on Escherichia coli K-12 and the location of the gene which mediates this effect. J.Gen.Microbiol. 130:2489-2495
- Viswanathan, V.K., J.M. Green, B.P. Nichols 1995. Kinetic characterization of 4-amino 4-deoxychorismate synthase from Escherichia coli. J.Bacteriol. 177:5918-5923
- Rayl, E.A., J.M. Green, B.P. Nichols 1996. Escherichia coli aminodeoxychorismate synthase: analysis of pabB mutations affecting catalysis and subunit association. Biochim.Biophys.Acta 1295:81-88