Site ompR
- Name: ompR
- Type: Gene
- Synonyms
b3405 MG1655 locus tag cry envZ ompB - Mnemonic: outer membrane protein
- Left End Point: 76.17
- Right End Point: 76.18
- Products:
OmpR, binding protein activated by P'ylation by EnvZ - Direction: <
- Properties:
Property Comment encodes NA-binding protein NULL regulatory gene NULL 2-compon.signal transd.gene EnvZ-OmpR system encodes signal transducer NULL - Priority: 1
- 4 Alleles of This Gene
ompR321(Am,polar) ompR739(del)::kan ompR792-YFP(::cat) ompR839(del)::FRT - External Database Links:
Host Site Page Links EcoGene.org EG10672 EcoliWiki ompR - Comment:
- activator protein for osmoregulation of porin protein genes ompC and ompF. when P'ylated by EnvZ it binds ompC promoter and activates transcription.
- References:
- Hall, M.N., T.J. Silhavy 1981. Genetic analysis of the ompB locus in Escherichia coli K-12. J.Mol.Biol. 151:1-15
- Hall, M.N., T.J. Silhavy 1981. The ompB locus and the regulation of the major outer membrane porin proteins of Escherichia coli K12. J.Mol.Biol. 146:23-43
- Taylor, R.K., M.N. Hall, L. Enquist, T.J. Silhavy 1981. Identification of OmpR: a positive regulatory protein controlling expression of the major outer membrane matrix porin proteins of Escherichia coli K-12. J.Bacteriol. 147:255-258
- Mizuno, T., E. Wurtzel, M. Inouye 1982. Cloning of the regulatory genes (ompR and envZ) for the matrix proteins of the Escherichia coli outer membrane. J.Bacteriol. 150:1462-1466
- Wurtzel, E., M.-Y. Chou, M. Inouye 1982. Osmoregulation of gene expression. I. DNA sequence of the ompR gene of the ompB operon of Escherichia coli and characterization of its gene product. J.Biol.Chem. 257:13685-13691
- Mizuno, T., E. Wurtzel, M. Inouye 1982. Osmoregulation of gene expression. II. DNA sequence of the envZ gene of the ompB operon of Escherichia coli and characterization of its gene product. J.Biol.Chem. 257:13692-13698
- Schweizer, H.P., T. Grussenmeyer, W. Boos 1982. Mapping of two ugp genes coding for the pho regulon-dependent sn-glycerol-3-phosphate transport system of Escherichia coli. J.Bacteriol. 150:1164-1171
- Comeau, D.E., K. Ikenaka, K. Tsung, M. Inoue 1985. Primary characterization of the protein products of the Escherichia coli ompB locus: structure and regulation of synthesis of the OmpR and EnvZ proteins. J.Bacteriol. 164:578-584
- Garrett, S., R.K. Taylor, T.J. Silhavy, M.L. Berman 1985. Isolation and characterization of DE ompB strains of Escherichia coli by a general method based on gene fusions. J.Bacteriol. 162:840-844
- Nara, F., S. Matsuyama, T. Mizuno, S. Mizushima 1986. Molecular analysis of mutant ompR genes exhibiting different phenotypes as to osmoregulation of the ompF and ompC genes of Escherichia coli. Mol.Gen.Genet. 202:194-199
- Mizuno, T., S. Mizushima 1987. Isolation and characterization of deletion mutants of ompR and envZ, regulatory genes for expression of the outer membrane proteins OmpC and OmpF in Escherichia coli. J.Biochem.(Tokyo) 101:387-396
- Tsui, P., L. Huang, M. Freundlich 1991. Integration host factor binds specifically to multiple sites in the ompB promoter of Escherichia coli and inhibits transcription. J.Bacteriol. 173:5800-5807
- Waukau, J., S. Forst 1992. Molecular analysis of the signaling pathway between EnvZ and OmpR in Escherichia coli. J.Bacteriol. 174:1522-1527
- Kanamaru, K., T. Mizuno 1992. Signal transduction and osmoregulation in Escherichia coli: a novel mutant of the positive regulator, OmpR, that functions in a phosphorylation-independent manner. J.Biochem.(Tokyo) 111:425-430
- Shin, S., C. Park 1995. Modulation of flagellar expression in Escherichia coli by acetyl phosphate and the osmoregulator OmpR. J.Bacteriol. 177:4696-4702
- Kato, N., M. Tsuzuki, H. Aiba, T. Mizuno 1995. Gene activation by the Escherichia coli positive regulator OmpR: a mutational study of the DNA-binding domain of OmpR. Mol.Gen.Genet. 248:399-406
- Lan, C.Y., M.M. Igo 1998. Differential expression of the OmpF and OmpC porin proteins in Escherichia coli K-12 depends upon the level of active OmpR. J.Bacteriol. 180:171-174
- Vidal, O., R. Longin, C. Prigent-Combaret, C. Dorel-Flamant, M. Hooreman, P. Lejeune 1998. Isolation of an Escherichia coli K-12 mutant strain able to form biofilms on inert surfaces: involvement of a new ompR allele that increases curli expression. J.
- Bergstrom, L.C., L. Qin, S.L. Harlocker, L.A. Egger, M. Inouye 1998. Hierarchical and co-operative binding of OmpR to a fusion construct containing the ompC and ompF upstream regulatory sequences of Escherichia coli. Genes Cells 3:777-788