Site nusB
- Name: nusB
- Type: Gene
- Synonyms
b0416 MG1655 locus tag groNB ssaD suppressor of secA; see Rajapandi and Oliver ssyB - Mnemonic: Nu (lambda protein) survival
- Left End Point: 9.36
- Right End Point: 9.37
- Products:
transcription termination L factor - Direction: >
- Priority: 1
- 2 Alleles of This Gene
nusB5 nusB776(del)::kan - External Database Links:
Host Site Page Links NCBI/GenBank X64395 EcoGene.org EG10666 EcoliWiki nusB - Comment:
- Selectable phenotype. Survival of induction of mutant LAM prophage; large colonies on plates with three different host-specific phage LAM. ssaD described by Oliver, below, shown not=secD by Gardel.
- References:
- Friedman, D., M. Baumann, L.S. Baron 1976. Cooperative effects of bacterial mutations affecting lambda N gene expression. I. Isolation and characterization of a nusB mutant. Virology 73:119-127
- Georgopoulos, C., J. Swindle, F. Keppel, M. Ballivet, R. Bisig, H.A. Eisen 1980. Studies on the E. coli groNB (nusB) gene which affects bacteriophage LAM N gene function. Mol.Gen.Genet. 179:55-61
- Ward, D.F., M.E. Gottesman 1981. The nus mutations affect transcription termination in Escherichia coli. Nature 292:212-215
- Ishii, S., E. Hatada, T. Maekawa, F. Imamoto 1984. Molecular cloning and nucleotide sequencing of the nusB gene of E. coli. Nucleic Acids Res. 12:4987-4995
- Swindle, J., J. Ajioka, D. Dawson, R. Myers, D. Carroll, C. Georgopoulos 1984. The nucleotide sequence of the Escherichia coli K12 nusB (groNB) gene. Nucleic Acids Res. 12:4977-4985
- Oliver, D.B. 1985. Identification of five new essential genes involved in the synthesis of a secreted protein in Echerichia coli. J.Bacteriol. 161:285-291
- Sharrock, R.A., R.L. Gourse, M. Nomura 1985. Defective antitermination of rRNA transcription and derepression of rRNA and tRNA synthesis in the nusB5 mutant of Escherichia coli. Proc.Natl.Acad.Sci.USA 82:5275-5279
- Gardel, C., S. Benson, J. Hunt, S. Michaeli, J.R. Beckwith 1987. secD, a new gene involved in protein export in Escherichia coli. J.Bacteriol. 169:1286-1290
- Taura, T., C. Ueguchi, K. Shiba, K. Ito 1992. Insertional disruption of the nusB (ssyB) gene leads to cold-sensitive growth of Escherichia coli and suppression of the secY24 mutation. Mol.Gen.Genet. 234:429-432
- Rajapandi, T., D. Oliver 1994. ssaD1, a suppressor of secA51(Ts) that renders growth of Escherichia coli cold sensitive, is an early amber mutation in the transcription factor gene nusB. J.Bacteriol. 176:4444-4447
- Court, D.L., T.A. Patterson, T. Baker, N. Costantino, X. Mao, D.I. Friedman 1995. Structural and functional analyses of the transcription-translation proteins NusB and NusE. J.Bacteriol. 177:2589-2591
- Mogridge, J., J. Greenblatt 1998. Specific binding of Escherichia coli ribosomal protein S1 to boxA transcriptional antiterminator RNA. J.Bacteriol. 180:2248-2252