Site metK
- Name: metK
- Type: Gene
- Synonyms
b2942 MG1655 locus tag - Mnemonic: Methionine
- Left End Point: 66.49
- Right End Point: 66.52
- Products:
methionine adenosyltransferase S-adenosylmethionine synthetase - Direction: >
- Properties:
Property Comment auxotrophy-amino acid NULL essential gene NULL - Priority: 1
- 3 Alleles of This Gene
metK110(ts) metK794-YFP(::cat) metK86 - External Database Links:
Host Site Page Links NCBI/GenBank K02129 EcoGene.org EG10589 EcoliWiki metK - Comment:
- Selectable phenotype. Ethionine resistance; glutamyl-gamma-methyl ester resistance ethionine, norleucine, a-methylmethionine resistance.
- References:
- Greene, R.C., J.V. Hunter, E.H. Coch 1973. Properties of metK mutants of Escherichia coli K-12. J.Bacteriol. 115:57-67
- Hafner, E.W., C.W. Tabor, H. Tabor 1977. Isolation of a metK mutant with a temperature-sensitive S-adenosylmethionine synthetase. J.Bacteriol. 132:832-840
- Kraus, J., D. Soll, K.B. Low 1979. Glutamyl-gamma-methyl ester acts as a methionine analogue in Escherichia coli: analogue resistant mutants map at the metJ and metK loci. Genet.Res. 33:49-55
- Boyle, S.M., G.D. Markham, E.W. Hafner, J.M. Wright, H. Tabor, C.W. Tabor 1984. Expression of the cloned genes encoding the putrescine biosynthetic enzymes and methionine adenosyltransferase of Escherichia coli. Gene 30:129-136
- Markham, G.D., J. DeParasis, J. Gatmaitan 1984. The sequence of metK, the structural gene for S-adenosylmethionine synthetase in Escherichia coli. J.Biol.Chem. 259:14505-14507
- Satishchandran, C., J.C. Taylor, G.D. Markham 1990. Novel Escherichia coli K-12 mutants impaired in S-adenosylmethionine synthesis. J.Bacteriol. 172:4489-4496
- Satishchandran, C., G.D. Markham, R.C. Moore, S.M. Boyle 1990. Locations of the speA, speB, speC, and metK genes on the physical map of Escherichia coli. J.Bacteriol. 172:4748-4748
- Ren, D., L.A. Bedzyk, S.M. Thomas, R.W. Ye, T.K. Wood 2004. Gene expression in Escherichia coli biofilms. Appl Microbiol Biotechnol 64:515-524