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Site djlA
- Name: djlA
- Type: Gene
- Synonyms
b0055 MG1655 locus tag - Mnemonic: DnaJ-like
- Left End Point: 1.24
- Right End Point: 1.25
- Products:
DnaJ-like chaperone protein - Direction: >
- Properties:
Property Comment encodes membrane protein inner membrane, unusual N-out, C-in topology - Priority: 0
- 1 Alleles of This Gene
djlA766(del)::kan - External Database Links:
Host Site Page Links EcoGene.org EG11570 EcoliWiki djlA - Comment:
- Proposed to dock and interact with var.of membrane proteins,incl.2-comp.syst. Short N-terminus facing periplasm and single transmemb.domain and large cytopl.domain. Mutants rapidly accum. suppressors.
- References:
- Clarke, D.J., A. Jacq, I.B. Holland 1996. A novel DnaJ-like protein in Escherichia coli inserts into the cytoplasmic membrane with a type III topology. Mol.Microbiol. 20:1273-1286
- Kelley, W.L., C. Georgopoulos 1997. Positive control of the two-component RcsC/B signal transduction network by DjIA: a member of the DnaJ family of molecular chaperones in Escherichia coli. Mol.Microbiol. 25:913-931
- Clarke, D.J., I.B. Holland, A. Jacq 1997. Point mutations in the transmembrane domain of DjIA, a membrane-linked DnaJ-like protein, abolish its function in promoting colanic acid production via the Rcs signal transduction pathway. Mol.Microbiol. 25:933
- Chen, M.H., S. Takeda, H. Yamada, Y. Ishii, T. Yamashino, T. Mizuno 2001. Characterization of the RcsC-->YojN-->RcsB phosphorelay signaling pathway involved in capsular synthesis in Escherichia coli. Biosci.Biotechnol.Biochem. 65:2364-2367