Site malF
- Name: malF
- Type: Gene
- Synonyms
b4033 MG1655 locus tag - Mnemonic: Maltose
- Left End Point: 91.42
- Right End Point: 91.45
- Products:
maltose transport complex, inner membrane-spanning subu. MalFGK inner membrane complex subu. - Direction: <
- Priority: 1
- 6 Alleles of This Gene
malF3089::Tn10 malF3180::Tn10kan malF55::Tn10 malF59::Tn5 malF64(Oc) malF729(del)::kan - External Database Links:
Host Site Page Links EcoGene.org EG10555 EcoliWiki malF - Comment:
- Selectable phenotype. Loss: 5-thiomaltose resistance. Regulatory, loss of catabolite repression: growth on maltose + a-methylgucoside.
- References:
- Saier, M.H., H. Straud, L.S. Massman, J.J. Judice, M.J. Newman, B.U. Feucht 1978. Permease-specific mutations in Salmonella typhimurium and Escherichia coli that release the glycerol, maltose, melibiose, and lactose transport systems from regulation by
- Froshauer, S., J.R. Beckwith 1984. The nucleotide sequence of the gene for malF protein, an inner membrane component of the maltose transport system of Escherichia coli. Repeated DNA sequences are found in the malE-malF intercistronic region. J.Biol.C
- McGovern, K., J. Beckwith 1991. Membrane insertion of the Escherichia coli MalF protein in cells with impaired secretion machinery. J.Biol.Chem. 266:20870-20876
- Traxler, B., C. Murphy 1996. Insertion of the polytopic membrane protein MalF is dependent on the bacterial secretion machinery. J.Biol.Chem. 271:12394-12400
- Ehrle, R., C. Pick, R. Ulrich, E. Hofmann, M. Ehrmann 1996. Characterization of transmembrane domains 6, 7, and 8 of MalF by mutational analysis. J.Bacteriol. 178:2255-2262
- Merino, G., H.A. Shuman 1997. Unliganded maltose-binding protein triggers lactose transport in an Escherichia coli mutant with an alteration in the maltose transport system. J.Bacteriol. 179:7687-7694