E. coli Genetic Resources at Yale
CGSC, The Coli Genetic Stock Center

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Site lamB

• Name: lamB
• Type: Gene
  Synonyms

  b4036	MG1655 locus tag

  
  
• Mnemonic: Lambda
• Left End Point: 91.51
• Right End Point: 91.54
  Products:

  phage lambda receptor protein

  maltose channel outer membrane protein

  maltoporin

  
  
• Direction: >
• Priority: 1
  8 Alleles of This Gene

  lamB2000(LamR)

  lamB204(Am)

  lamB20::Tn5

  lamB60::Tn10

  lamB63

  lamB732(del)::kan

  lamB832(del)::FRT

  mal+([K-12])(LamS)

  
  
• External Database Links:

  Host Site	Page Links
  NCBI/GenBank	M16643
  NCBI/GenBank	V00297
  EcoGene.org	EG10528
  EcoliWiki	lamB

  
  
• Comment:
  • Selectable phenotype. Loss or change: phage LAM resistance.
• References:
  • Thirion, J.P., M. Hofnung 1972. On some genetic aspects of phage lambda resistance in E. coli K12. Genetics 71:207-216
  
  
  • Hedgpeth, J., J.M. Clement, C. Marchal, D.M. Perrin, M. Hofnung 1980. DNA sequence encoding the NH2-terminal peptide involved in transport of lambda receptor, an Escherichia coli secretory protein. Proc.Natl.Acad.Sci.USA 77:2621-2625
  
  
  • Emr, S.D., J. Hedgepeth, J.M. Clement, T.J. Silhavy, M. Hofnung 1980. Sequence analysis of mutations that prevent export of LAM receptor, an Escherichia coli outer membrane protein. Nature 285:82-85
  
  
  • Colonna, B., M. Hofnung 1981. rho mutations restore lamB expression in E. coli K12 strains with an inactive malB region. Mol.Gen.Genet. 184:479-483
  
  
  • Braun-Breton, C., M. Hofnung 1981. In vivo and in vitro functional alterations of the bacteriophage lambda receptor to lamB missense mutants of Escherichia coli K-12. J.Bacteriol. 148:845-852
  
  
  • Schwartz, M., M. Roa, M. Debarbouille 1981. Mutations that affect lamB gene expression at a posttranscriptional level. Proc.Natl.Acad.Sci.USA 78:2937-2941
  
  
  • Hofnung, M., E. Lepouce, C. Braun-Breton 1981. General method for fine mapping of the Escherichia coli K-12 lamB gene: localization of missense mutations affecting bacteriophage lambda adsorption. J.Bacteriol. 148:853-860
  
  
  • Clement, J.M., M. Hofnung 1981. Gene sequence of the LAM receptor, an outer membrane protein of E. coli K-12. Cell 27:507-514
  
  
  • Emr, S.D., S. Hanley-Way, T.J. Silhavy 1981. Suppressor mutations that restore export of a protein with a defective signal sequence. Cell 23:79-88
  
  
  • Death, A., L. Notley, T. Ferenci 1993. Derepression of LamB protein facilitates outer membrane permeation of carbohydrates into Escherichia coli under conditions of nutrient stress. J.Bacteriol. 175:1475-1483
  
  
  • Charbit, A., C. Andersen, J. Wang, B. Schiffler, V. Michel, R. Benz, M. Hofnung 2000. In vivo and in vitro studies of transmembrane beta-strand deletion, insertion or substitution mutants of the Escherichia coli K-12 maltoporin. Mol.Microbiol. 35:777-7
  
  
  • Van Gelder, P., R. Dutzler, F. Dumas, R. Koebnik, T. Schirmer 2001. Sucrose transport through maltoporin mutants of Escherichia coli. Protein Engineering 14:943-948