Site dxr
- Name: dxr
- Type: Gene
- Synonyms
b0173 MG1655 locus tag ispC other isoprenoid pathway workers yaeM temporary name - Mnemonic: deoxyxylulose-phosphate reductoisomerase
- Left End Point: 4.17
- Right End Point: 4.20
- Products:
deoxyxylulose-P reductoisomerase 1-deoxy-D-xylulose 5-phosphate reductoisomerase 2-C-methylerythritol-4P synthase - Direction: >
- Properties:
Property Comment auxotrophy-other for 2-C-methylerythritol, free alcohol of precursor of nonmevalonate path to isopentenyl diphosphate - Priority: 0
- External Database Links:
Host Site Page Links EcoGene.org EG12715 EcoliWiki dxr - Comment:
- terpenoid biosynthesis. nonmevalonate pathway. DXP to 2-C-methylerythritol-4-P.
- References:
- Takahashi, S., T. Kuzuyama, H. Watanabe, H. Seto 1998. A 1-deoxy-D-xylulose 5-phosphate reductoisomerase catalyzing the formation of 2-C-methyl-D-erythritol 4-phosphate in an alternative nonmevalonate pathway for terpenoid biosynthesis. Proc.Natl.Acad.
- Kuzuyama, T., S. Takahashi, H. Seto 1999. Construction and characterization of Escherichia coli disruptants defective in the yaeM gene. Biosci.Biotechnol.Biochem. 63:776-778