Site glnU
- Name: glnU
- Type: Gene
- Synonyms
$su_B$ when mutates to OS or AS b0670 MG1655 locus tag sufG Kohno and Roth, shown to be tRNAGln1 by O'Connor supB su_B+ - Mnemonic: Glutamine
- Left End Point: 15.00
- Right End Point: 15.01
- Products:
glutamine tRNA1 - Direction: <
- Properties:
Property Comment tRNA gene tRNA1 duplicate gene tandem duplication, see also glnU - Priority: 1
- 1 Alleles of This Gene
glnU69(OS) - External Database Links:
Host Site Page Links EcoGene.org EG30028 EcoliWiki glnU - Comment:
- sufG alleles are insertions in the anticodon loop allowing CAAA decoding, thus suppressing +1 frameshifts
- References:
- Inokuchi, H., F. Yamao, H. Sakano, H. Ozeki 1979. Identification of transfer RNA suppressors in Escherichia coli. I. Amber suppressor su^+2, and anticodon mutant of tRNA_2^Gln. J.Mol.Biol. 132:649-662
- Nakajima, N., H. Ozeki, Y. Shimura 1981. Organization and structure of an E. coli tRNA operon containing seven tRNA genes. Cell 23:239-249
- Nakajima, N., H. Ozeki, Y. Shimura 1982. In vitro transcription of the supB-E tRNA operon of Escherichia coli. J.Biol.Chem. 257:11113-11120
- Fournier, M.J., H. Ozeki 1985. Structure and organization of the transfer ribonucleic acid genes of Escherichia coli K-12. Microbiol.Rev. 49:379-397
- Plumbridge, J.A. 1987. Organization of the Escherichia coli chromosome between genes glnS and glnU, V. Mol.Gen.Genet. 209:618-620
- Eggertsson, G., D. Soll 1988. Transfer ribonucleic acid-mediated suppression of termination codons in Escherichia coli. Microbiol.Rev. 52:354-374
- Komine, Y., T. Adachi, K. Inokuchi, H. Ozeki 1990. Genomic organization and physical mapping of the transfer RNA genes in Escherichia coli K12. J.Mol.Biol. 212:579-598
- O'Connor, M. 2002. Insertions in the anticodon loop of tRNA1Gln(sufG) and tRNA(Lys) promote quadruplet decoding of CAAA. Nucleic Acids Res. 30:1985-1990