Site lpxC
- Name: lpxC
- Type: Gene
- Synonyms
asmB Kloser et al. mutant suppressing ompF assembly-defective mutants b0096 MG1655 locus tag envA - Mnemonic: lipid A eXpression
- Left End Point: 2.30
- Right End Point: 2.32
- Products:
UDP-3-O(R-3-hydroxymyristoyl)GlcNAc deacetylase - Direction: >
- Properties:
Property Comment essential gene NULL - Priority: 1
- 1 Alleles of This Gene
lpxC101 - External Database Links:
Host Site Page Links NCBI/GenBank M19211 EcoGene.org EG10265 EcoliWiki lpxC - Comment:
- Cell envelope and cell separation. Part of cell-envelope.
- References:
- Lutkenhaus, J., H.C. Wu 1980. Determination of transcriptional units and gene products from the ftsA region of Escherichia coli. J.Bacteriol. 143:1281-1288
- Metzer, E., Y.S. Halpern 1980. Mutations affecting the regulation of gamma-aminobutyrate utilization in Escherichia coli K-12. Curr.Microbiol. 4:51-55
- Lutkenhaus, J., H. Wolf-Watz, W.D. Donachie 1980. Organization of genes in the ftsA-envA region of the Escherichia coli genetic map and identification of a new fts locus (ftsZ). J.Bacteriol. 142:615-620
- Sullivan, N.F., W.D. Donachie 1984. Transcriptional organization within an Escherichia coli cell division gene cluster: direction of transcription of the cell separation gene envA. J.Bacteriol. 160:724-732
- Nahlik, M.S., T.P. Fleming, M.A. McIntosh 1987. Cluster of genes controlling synthesis and activation of 2,3-dihydroxybenzoic acid in production of enterobactin in Escherichia coli. J.Bacteriol. 169:4163-4170
- Beall, B., J. Lutkenhaus 1987. Sequence analysis, transcriptional organization, and insertional mutagenesis of the envA gene of Escherichia coli. J.Bacteriol. 169:5408-5415
- Jung, H.K., F. Ishino, M. Matsuhashi 1989. Inhibition of growth of ftsQ, ftsA, and ftsZ mutant cells of Escherichia coli by amplification of a chromosomal region encompassing closely aligned cell division and cell growth genes. J.Bacteriol. 171:6379-63
- Schnaitman, CA, JD Klena 1993. Genetics of lipopolysaccharide biosynthesis in enteric bacteria. Microbiol. Rev. 57(3):655-82.
- Young, K., L.L. Silver, D. Bramhill, P. Cameron, S.S. Eveland, C.R. Raetz, S.A. Hyland, M.S. Anderson 1995. The envA permeability/cell division gene of Escherichia coli encodes UDP-3-O-(R-3-hydroxymyristoyl)-N-acetylglucosamine deacetylase. J.Biol.Chem
- Kloser, A.W., M.W. Laird, R. Misra 1996. asmB, a suppressor locus for assembly-defective OmpF mutants of Escherichia coli, is allelic to envA (lpxC). J.Bacteriol. 178:5138-5143
- Sorensen, P.G., J. Lutkenhaus, K. Young, S.S. Eveland, M.S. Anderson, C.R. Raetz 1996. Regulation of UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase in Escherichia coli. The second enzymatic step of lipid a biosynthesis. J.Biol.Chem. 271