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Site entC
- Name: entC
- Type: Gene
- Synonyms
b0593 MG1655 locus tag - Mnemonic: Enterochelin, enterobactin
- Left End Point: 13.45
- Right End Point: 13.48
- Products:
isochorismate synthetase - Direction: >
- Priority: 1
- 1 Alleles of This Gene
entC731(del)::kan - External Database Links:
Host Site Page Links NCBI/GenBank M24142 EcoGene.org EG10261 EcoliWiki entC - Comment:
- chorismate to isochorismate. nuc.simil. of ca.45% with trpE and pabB, two other chor.-binding enz., also prot seq. simil.
- References:
- Laird, A.J., I.G. Young 1980. Tn5 mutagenesis of the enterochelin gene cluster of Escherichia coli. Gene 11:359-366
- Laird, A.J., D.W. Ribbons, G.C. Woodrow, I.G. Young 1980. Bacteriophage Mu-mediated gene transposition and in vitro cloning of the enterochelin gene cluster of Escherichia coli. Gene 11:347-357
- Fleming, T.P., M.S. Nahlik, M.A. McIntosh 1983. Regulation of enterobactin iron transport in Escherichia coli: characterization of ent::Mu d(Ap^r lac) operon fusions. J.Bacteriol. 156:1171-1177
- Pickett, C.L., L. Hayes, C.F. Earhart 1984. Molecular cloning of the Escherichia coli K-12 entACGBE genes. FEMS Microbiol.Lett. 24:77-80
- Ozenberger, B.A., M.S. Nahlik, M.A. McIntosh 1987. Genetic organization of multiple fep genes encoding ferric enterobactin transport functions in Escherichia coli. J.Bacteriol. 169:3638-3646
- Nahlik, M.S., T.P. Fleming, M.A. McIntosh 1987. Cluster of genes controlling synthesis and activation of 2,3-dihydroxybenzoic acid in production of enterobactin in Escherichia coli. J.Bacteriol. 169:4163-4170
- Nahlik, M.S., T.J. Brickman, B.A. Ozenberger, M.A. McIntosh 1989. Nucleotide sequence and transcriptional organization of the Escherichia coli enterobactin biosynthesis cistrons entB and entA. J.Bacteriol. 171:784-790
- Ozenberger, B.A., T.J. Brickman, M.A. McIntosh 1989. Nucleotide sequence of Escherichia coli isochorismate synthetase gene entC and evolutionary relationship of isochorismate synthetase and other chorismate-utilizing enzymes. J.Bacteriol. 171:775-783
- Walsh, C.T., J. Liu, F. Rusnak, M. Sakaitani 1990. Molecular studies on enzymes in chorismate metabolism and the enterobactin biosynthetic pathway. Chem. Rev. 90:1105-1129
- Liu, J., N. Quinn, G.A. Berchtold, C.T. Walsh 1990. Overexpression, purification, and characterization of isochorismate synthase (EntC), the first enzyme involved in the biosynthesis of enterobactin from chorismate. Biochemistry 29:1417-1425