Pay an invoice 
Site dnaG
- Name: dnaG
- Type: Gene
- Synonyms
b3066 MG1655 locus tag dnaP parB sdgA - Mnemonic: DNA
- Left End Point: 69.17
- Right End Point: 69.20
- Products:
primase - Direction: >
- Properties:
Property Comment DNA biosynthesis NULL affects cell division/growth NULL - Priority: 1
- 5 Alleles of This Gene
dnaG18 dnaG3(ts) dnaG308(ts) dnaG399(ts) dnaG757(del)::kan - External Database Links:
Host Site Page Links EcoGene.org EG10239 EcoliWiki dnaG - Comment:
- Missense mutations in the 3' end do not abolish primase activity, but confer the par (partition: chromosome-seg-defective) phenotype (Versalovic and Lupski).
- References:
- Gross, C.A., F.R. Blattner, W.E. Taylor, P.A. Lowe, R.R. Burgess 1979. Isolation and characterization of transducing phage coding for a subunit of Escherichia coli RNA polymerase. Proc.Natl.Acad.Sci.USA 76:5789-5793
- Nakamura, Y. 1980. Hybrid plasmid carrying Escherichia-coli genes for primase (dnaG) and RNA polymerase sigma factor (rpoD); gene organization and control of their expression. Mol.Gen.Genet. 178:487-497
- Smiley, B.L., J.R. Lupski, P.S. Svec, R. MacMacken, G.N. Godson 1982. Sequences of the Escherichia coli dnaG primase gene and regulation of its expression. Proc.Natl.Acad.Sci.USA 79:4550-4554
- Rowen, L., J. Kobori, S. Scherer 1982. Cloning of bacterial DNA replication genes in bacteriophage lambda. Mol.Gen.Genet. 187:501-509
- Lupski, J.R., B.L. Smiley, F.R. Blattner, G.N. Godson 1982. Cloning and characterization of the Escherichia coli chromosomal region surrounding the dnaG gene, with a correlated physical and genetic map of dnaG generated via transposon Tn5 mutagenesis.
- Wold, M.S., R. McMacken 1982. Regulation of expression of the Escherichia coli dnaG gene and amplification of the dnaG primase. Proc.Natl.Acad.Sci.USA 79:4907-4911
- Burton, Z.F., C.A. Gross, K. Watanabe, R.R. Burgess 1983. The operon that encodes the sigma subunit of RNA polymerase also encodes ribosomal protein S21 and DNA primase in E. coli K12. Cell 32:335-349
- Lupski, J.R., B.L. Smiley, G.N. Godson 1983. Regulation of the rpsU-dnaG-rpoD macromolecular synthesis operon and the initiation of DNA replication in Escherichia coli K-12. Mol.Gen.Genet. 189:48-57
- Lupski, J.R., A.A. Ruiz, G.N. Godson 1984. Promotion, termination and anti-termination of the rpsU-dnaG-rpoD macromolecular synthesis operon of E. coli K-12. Mol.Gen.Genet. 195:391-401
- Taylor, W.E., D.B. Straus, A.D. Grossman, Z.F. Burton, C.A. Gross, R.R. Burgess 1984. Transcription from a heat-inducible promoter causes heat shock regulation of the sigma subunit of E. coli RNA polymerase. Cell 38:371-381
- Murakami, H., T. Nagata, W. Schwarz, C. Wada, T. Yura 1985. Novel dnaG mutation in a dnaP mutant of Escherichia coli. J.Bacteriol. 162:830-832
- Norris, V.J., T. Alliotte, A. Jaffe, R. D'Ari 1986. DNA replication termination in Escherichia coli parB (a dnaG allele), parA and gyrB mutants affected in DNA distribution. J.Bacteriol. 168:494-504
- Nakayama, N., M.W. Bond, A. Miyajima, J. Kobori, K.-I. Arai 1987. Structure of Escherichia coli dnaC. Identification of a cystein residue possibly involved in association with dnaB protein. J.Biol.Chem. 262:10475-10480
- Tougu, K., K.J. Marians 1996. The interaction between helicase and primase sets the replication fork clock. J.Biol.Chem. 271:21398-21405
- Versalovic, J., J.R. Lupski 1997. Missense mutations in the 3' end of the Escherichia coli dnaG gene do not abolish primase activity but do confer the chromosome-segregation-defective (par) phenotype. Microbiology 143:585-594