Site dgsA
- Name: dgsA
- Type: Gene
- Synonyms
b1594 MG1655 locus tag mlc Hosono et al., for "makes large colonies" - Mnemonic: D-Glucosamine
- Left End Point: 35.90
- Right End Point: 35.92
- Products:
regulator of manXYZ - Direction: <
- Priority: 1
- 1 Alleles of This Gene
dgsA742(del)::kan - External Database Links:
Host Site Page Links EcoGene.org EG13156 EcoliWiki dgsA - Comment:
- Function of enzyme IIA/IIB of phosphotransferase system. Selectable phenotype. Loss; in ptsG-: growth on glucosamine anerobically. Binds NagC operators, regulates expression of manX of PTS system
- References:
- Roehl, R.A., R. Vinopal 1980. Genetic locus, distant from ptsM, affecting enzyme IIA/IIB function in Escherichia coli K-12. J.Bacteriol. 142:120-130
- Morris, P.W., J.P. Binkley, J.M. Henson, P. Kuempel 1985. Cloning and location of the dgsA gene of Escherichia coli. J.Bacteriol. 163:785-786
- Hosono, K., H. Kakuda, S. Ichihara 1995. Decreasing accumulation of acetate in a rich medium by Escherichia coli on introduction of genes on a multicopy plasmid. Biosci. Biotechnol. Biochem. 59:256-261
- Decker, K., J. Plumbridge, W. Boos 1998. Negative transcriptional regulation of a positive regulator: the expression of malT, encoding the transcriptional activator of the maltose regulon of Escherichia coli, is negatively controlled by Mlc. Mol.Microb
- Plumbridge, J. 1998. Control of the expression of the manXYZ operon in Escherichia coli: Mlc is a negative regulator of the mannose PTS. Mol.Microbiol. 27:369-380
- Shin, D., S. Lim, Y.J. Seok, S. Ryu 2001. Heat shock RNA polymerase (E sigma(32)) is involved in the transcription of mlc and crucial for induction of the Mlc regulon by glucose in Escherichia coli. J.Biol.Chem. 276:25871-25875