Site tnaA
- Name: tnaA
- Type: Gene
- Synonyms
b3708 MG1655 locus tag ind tnaR - Mnemonic: tryptophanase
- Left End Point: 83.77
- Right End Point: 83.80
- Products:
tryptophanase - Direction: >
- Priority: 1
- 9 Alleles of This Gene
tnaA1 tnaA3 tnaA300([])::Tn10 tnaA4 tnaA5 tnaA6 tnaA739(del)::kan tnaA791-YFP(::cat) tnaA7::Tn10 - External Database Links:
Host Site Page Links NCBI/GenBank K00032 NCBI/GenBank M11990 EcoGene.org EG11005 EcoliWiki tnaA - Comment:
- Selectable phenotype. Constitutive: growth on tryptophan at 13 degrees C. In DE trp-: growth on glucose + indole + 5-methyl- tryptophan. Duplication in DE trp-: growth on gluconate + indole.
- References:
- Ng, H., T.K. Gartner 1963. Selection of mutants of Escherichia coli constitutive for tryptophanase. J.Bacteriol. 85:245-246
- Newton, W.A., E.E. Snell 1965. Formation and interrelationships of tryptophanase and tryptophan synthetases in Escherichia coli. J.Bacteriol. 89:355-364
- Watanabe, T., E.E. Snell 1972. Reversibility of the tryptophanase reaction: synthesis of tryptophan from indole, pyruvate, and ammonia. Proc.Natl.Acad.Sci.USA 69:1086-1090
- Yudkin, M. 1977. Unstable mutations that relieve catabolite repression of tryptophanase synthesis by Escherichia coli. J.Bacteriol. 130:57-61
- Miki, T., M. Kimura, S. Hiraga, T. Nagata, T. Yura 1979. Cloning and physical mapping of the dnaA region of the Escherichia coli chromosome. J.Bacteriol. 140:817-824
- von Meyenburg, K., F.G. Hansen, E. Riise, H.E.N. Bergmans, M. Meijer, W. Messer 1980. The origin of replication, oriC, of the Escherichia coli chromosome: genes near oriC and construction of oriC deletion mutations. In B. Alberts, and C.F. Fox (ed),
- Deeley, M.C., C. Yanofsky 1981. Nucleotide sequence of the structural gene for tryptophanase of Escherichia coli K-12. J.Bacteriol. 147:787-796
- Stewart, V.J., R. Landick, C. Yanofsky 1986. Rho-dependent transcription termination in the tryptophanase operon leader region of Escherichia coli K-12. J.Bacteriol. 166:217-223
- Burland, V.D., G. Plunkett, D.L. Daniels, F.R. Blattner 1993. DNA sequence and analysis of 136 kilobases of the Escherichia coli genome: organizational symmetry around the origin of replication. Genomics 16:551-561
- Blankenhorn, D., J. Phillips, J. Slonczewski 1999. Acid- and base-induced proteins during aerobic and anaerobic growth of Escherichia coli revealed by two-dimensional gel electrophoresis. J.Bacteriol. 181:2209-2216
- Phillips, R.S., N. Johnson, A.V. Kamath 2002. Formation in vitro of hybrid dimers of H463F and Y74F mutant Escherichia coli tryptophan indole-lyase rescues activity with L-tryptophan. Biochemistry 41:4012-4019