Site spoT
- Name: spoT
- Type: Gene
- Synonyms
b3650 MG1655 locus tag - Mnemonic: spot ("magic spot")
- Left End Point: 82.34
- Right End Point: 82.39
- Products:
guanosine 5'-diphosphate, 3'-diphosphate pyrophosphatase - Direction: >
- Properties:
Property Comment regulatory gene NULL - Priority: 1
- 5 Alleles of This Gene
spoT0 spoT1 spoT11 spoT791-YFP(::cat) spoT802 - External Database Links:
Host Site Page Links NCBI/GenBank M24503 EcoGene.org EG10966 EcoliWiki spoT - Comment:
- References:
- Sarubbi, E., K.E. Rudd, M. Cashel 1988. Basal ppGpp level adjustments shown by new spoT mutants affect steady state growth rates and rrnA ribosomal promoter regulation in Escherichia coli. Mol.Gen.Genet. 213:214-222
- Sarubbi, E., K.E. Rudd, H. Xiao, K. Ikehara, M. Kalman, M. Cashel 1989. Characterization of the spoT gene of Escherichia coli. J.Biol.Chem. 264:15074-15082
- Metzger, S., E. Sarubbi, G. Glaser, M. Cashel 1989. Protein sequences encoded by the relA and the spoT genes of Escherichia coli are interrelated. J.Biol.Chem. 264:9122-9125
- Xiao, H, M Kalman, K Ikehara, S Zemel, G Glaser, M Cashel 1991. Residual guanosine 3',5'-bispyrophosphate synthetic activity of relA null mutants can be eliminated by spoT null mutations. J. Biol. Chem. 266(9):5980-90.
- Murray, K.D., H. Bremer 1996. Control of spoT-dependent ppGpp synthesis and degradation in Escherichia coli. J.Mol.Biol. 259:41-57
- Gong, L., K. Takayama, S. Kjelleberg 2002. Role of spoT-dependent ppGpp accumulation in the survival of light-exposed starved bacteria. Microbiology 148:559-570