Site tus
- Name: tus
- Type: Gene
- Synonyms
b1610 MG1655 locus tag tau Kobayishi et al. - Mnemonic: terminus utilization substance
- Left End Point: 36.26
- Right End Point: 36.28
- Products:
DNA sequence-specific contra-helicase Ter-binding protein - Direction: >
- Priority: 1
- 1 Alleles of This Gene
tus-758(del)::kan - External Database Links:
Host Site Page Links EcoGene.org EG11038 EcoliWiki tus - Comment:
- DNA-binding protein; inhibition of replication
- References:
- Hill, T.M., B.J. Kopp, P. Kuempel 1988. Termination of DNA replication in Escherichia coli requires a trans-acting factor. J.Bacteriol. 170:662-668
- Pelletier, A.J., T.M. Hill, P. Kuempel 1988. Location of sites that inhibit progression of replication forks in the terminus region in Escherichia coli. J.Bacteriol. 170:4293-4298
- Hidaka, M., T. Kobayashi, S. Takenaka, H. Takeya, T. Horiuchi 1989. Purification of a DNA replication terminus (ter) site-binding protein in Escherichia coli and identification of the structural gene. J.Biol.Chem. 264:21031-21037
- Kuempel, P., A.J. Pelletier, T.M. Hill 1989. tus and the terminators: the arrest of replication in prokaryotes. Cell 59:581-583
- Khatri, G.S., T. MacAllister, P.R. Sista, D. Bastia 1989. The replication terminator protein of E. coli is a DNA sequence-specific contra-helicase. Cell 59:667-674
- Kobayashi, T., M. Hidaka, T. Horiuchi 1989. Evidence of a ter specific binding protein essential for the termination reaction of DNA replication in Escherichia coli. EMBO J. 8:2435-2441
- Hill, T.M., M.L. Tecklenburg, A.J. Pelletier, P. Kuempel 1989. tus, the transacting gene required for termination of DNA replication in Escherichia coli, encodes a DNA-binding protein. Proc.Natl.Acad.Sci.USA 86:1593-1597
- Dasgupta, S., R. Bernander, K. Nordstrom 1991. In vivo effect of the tus mutation on cell division in an Escherichia coli strain where chromosome replication is under the control of plasmid R1. Res.Microbiol. 142:177-180
- Roecklein, B.A., P.L. Kuempel 1992. In vivo characterization of tus gene expression in Escherichia coli. Mol.Microbiol. 6:1655-1661