Site nfnB
- Name: nfnB
- Type: Gene
- Synonyms
b0578 MG1655 locus tag nfsB nfsI ntr - Mnemonic: nitrofurantoin
- Left End Point: 13.02
- Right End Point: 13.03
- Products:
minor nitroreductase, oxygen-insensitive - Direction: >
- Priority: 1
- 1 Alleles of This Gene
nfnB787(del)::kan - External Database Links:
Host Site Page Links EcoGene.org EG20151 EcoliWiki nfnB - Comment:
- Sensitivity to nitrofurantoin. Selectable phenotype. Nitrofurantoin resistance.
- References:
- McCalla, D.R., C. Kaiser, M.H.L. Green 1978. Genetics of nitrofurazone resistance in Escherichia coli. J.Bacteriol. 133:10-16
- Breeze, A.S., E.E. Obaseiki-Ebor 1983. Mutations in nitrofurantoin and nitrofurazone resistance in Escherichia coli K-12. J.Gen.Microbiol. 129:99-103
- Sastry, S.S., R. Jayaraman 1984. Nitrofurantoin-resistant mutants of Escherichia coli: isolation and mapping. Mol.Gen.Genet. 196:379-380
- Michael, N.P., J.K. Brehm, G.M. Anlezark, N.P. Minton 1994. Physical characterisation of the Escherichia coli B gene encoding nitroreductase and its over-expression in Escherichia coli K12. FEMS Microbiol.Lett. 124:195-202
- Zenno, S., H. Koike, M. Tanokura, K. Saigo 1994. Identification of the gene encoding the NfsB/NfnB nitroreductase associated with a low level of flavin reductase activity in Escherichia coli K12. GenBank submission D2541:4
- Zenno, S., H. Koike, M. Tanokura, K. Saigo 1996. Gene cloning, purification, and characterization of NfsB, a minor oxygen-insensitive nitroreductase from Escherichia coli, similar in biochemical properties to FRase I, the major flavin reductase in Vibr