Site rfaS
- Name: rfaS
- Type: Gene
- Synonyms
b3629 MG1655 locus tag waaS - Mnemonic: Rough
- Left End Point: 81.95
- Right End Point: 81.97
- Direction: <
- Priority: 0
- 1 Alleles of This Gene
rfaS740(del)::kan - External Database Links:
Host Site Page Links EcoGene.org EG11350 EcoliWiki rfaS - Comment:
- Mutations change LPS core, but do not affect attachment of O antigen. Functional gene not present in Salmonella (Klena et al.1993 ref.)
- References:
- Austin, E.A., J.F. Graves, L.A. Hite, C. Parker, C.A. Schnaitman 1990. Genetic analysis of lipopolysaccharide core biosynthesis by Escherichia coli K-12: insertion mutagenesis of the rfa locus. J.Bacteriol. 172:5312-5325
- Schnaitman, C.A., C. Parker, J.D. Klena, E. Pradel, N.B. Pearson, K.E. Sanderson, P.R. MacLachlan 1991. Physical maps of the rfa loci of Escherichia coli K-12 and Salmonella typhimurium. J.Bacteriol. 173:7410-7411
- Pradel, E., C. Parker, C.A. Schnaitman 1992. Structures of the rfaB, rfaI, rfaJ, and rfaS genes of Escherichia coli K-12 and their roles in assembly of the lipopolysaccharide core. J.Bacteriol. 174:4736-4745
- Klena, J.D., R.S. Ashford, C.A. Schnaitman 1992. Role of Escherichia coli K-12 rfa genes and the rfp gene of Shigella dysenteriae 1 in generation of lipopolysaccharide core heterogeneity and attachment of O antigen. J.Bacteriol. 174:7297-7307
- Roncero, C., M.J. Casadaban 1992. Genetic analysis of the genes involved in synthesis of the lipopolysaccharide core in Escherichia coli K-12. J.Bacteriol. 174:3250-3260
- Klena, J.D., E. Pradel, C.A. Schnaitman 1993. The rfaS gene, which is involved in production of a rough form of lipopolysaccharide core in Escherichia coli K-12 is not present in the rfa cluster of Salmonella typhimurium LT2. J.Bacteriol. 175:1524-1527
- Schnaitman, CA, JD Klena 1993. Genetics of lipopolysaccharide biosynthesis in enteric bacteria. Microbiol. Rev. 57(3):655-82.
- Klena, J.D., C.A. Schnaitman 1994. Genes for TDP-rhamnose synthesis affect the pattern of lipopolysaccharide heterogeneity in Escherichia coli K-12. J.Bacteriol. 176:4003-4010