Site rfa
- Name: rfa
- Type: Cluster
- Synonyms
con lps phx - Mnemonic: Rough
- Left End Point: 81.69
- Right End Point: 82.00
- Direction: <
- Priority: 1
- 11 Alleles of This Gene
rfa-1 rfa-11 rfa-209::Tn10 rfa-21 rfa-210::Tn10 rfa-230 rfa-300 rfa-302 rfa-308 rfa-31 rfa-32 - External Database Links:
Host Site Page Links NCBI/GenBank M95398 - Comment:
- LPS core biosyn. and O-antigen attachment. see pers.comm. K.Sanderson and Carl Schnaitman 1/5/89 in corr. file. Sel.pheno. Loss: phage res.; ampic.res. Two operons.
- References:
- Makela, P.H., B. Stocker 1969. Genetics of polysaccharide biosynthesis. Annu.Rev.Genet. 3:291-322
- Eriksson-Grennberg, K.G., K. Nordstrom, P. Englund 1971. Resistance of Escherichia coli to penicillins. IX. Genetics and physiology of Class II ampicillin-resistant mutants that are galactose negative or sensitive to Bacteriophage C21, or both. J.Bact
- Austin, E.A., J.F. Graves, L.A. Hite, C. Parker, C.A. Schnaitman 1990. Genetic analysis of lipopolysaccharide core biosynthesis by Escherichia coli K-12: insertion mutagenesis of the rfa locus. J.Bacteriol. 172:5312-5325
- Schnaitman, C.A., C. Parker, J.D. Klena, E. Pradel, N.B. Pearson, K.E. Sanderson, P.R. MacLachlan 1991. Physical maps of the rfa loci of Escherichia coli K-12 and Salmonella typhimurium. J.Bacteriol. 173:7410-7411
- Pradel, E., C.A. Schnaitman 1991. Effect of rfaH (sfrB) and temperature on expression of rfa genes of Escherichia coli K-12. J.Bacteriol. 173:6428-6431
- Parker, C., A.W. Kloser, C.A. Schnaitman, M.A. Stein, S. Gottesman, B.W. Gibson 1992. Role of the rfaG and rfaP genes in determining the lipopolysaccharide core structure and cell surface properties of Escherichia coli K-12. J.Bacteriol. 174:2525-2538
- Clementz, T. 1992. The gene coding for 3-deoxy-manno-octulosonic acid transferase and the rfaQ gene are transcribed from divergently arranged promoters in Escherichia coli. J.Bacteriol. 174:7750-7756
- Parker, C., E. Pradel, C.A. Schnaitman 1992. Identification and sequences of the lipopolysaccharide core biosynthetic genes rfaQ, rfaP,and rfaG of Escherichia coli K-12. J.Bacteriol. 174:930-934
- Roncero, C., M.J. Casadaban 1992. Genetic analysis of the genes involved in synthesis of the lipopolysaccharide core in Escherichia coli K-12. J.Bacteriol. 174:3250-3260
- Klena, J.D., R.S. Ashford, C.A. Schnaitman 1992. Role of Escherichia coli K-12 rfa genes and the rfp gene of Shigella dysenteriae 1 in generation of lipopolysaccharide core heterogeneity and attachment of O antigen. J.Bacteriol. 174:7297-7307
- Schnaitman, CA, JD Klena 1993. Genetics of lipopolysaccharide biosynthesis in enteric bacteria. Microbiol. Rev. 57(3):655-82.
- Klena, J.D., C.A. Schnaitman 1994. Genes for TDP-rhamnose synthesis affect the pattern of lipopolysaccharide heterogeneity in Escherichia coli K-12. J.Bacteriol. 176:4003-4010
- Sofia, H.J., V.D. Burland, D.L. Daniels, G. Plunkett, F.R. Blattner 1994. Analysis of the Escherichia coli genome. V. DNA sequence of the region from 76.0 to 81.5 minutes. Nucleic Acids Res. 22:2576-2586