Pay an invoice 
Site eco
- Name: eco
- Type: Gene
- Synonyms
b2209 MG1655 locus tag - Mnemonic: ecotin, serine protease inhibitor
- Left End Point: 49.62
- Right End Point: 49.63
- Products:
ecotin - Direction: >
- Priority: 0
- 1 Alleles of This Gene
eco-762(del)::kan - External Database Links:
Host Site Page Links EcoGene.org EG10255 EcoliWiki eco - Comment:
- References:
- Chung, C.H., H.E. Ives, S. Almeda, A.L. Goldberg 1983. Purification from Escherichia coli of a perimplasmic protein that is a potent inhibitor of pancreatic proteases. J.Biol.Chem. 258:11032-11038
- McGrath, M.E., W.M. Hines, J.A. Sakanari, R.J. Fletterick, C.S. Craik 1991. The sequence and reactive site of ecotin. A general inhibitor of pancreatic serine proteases. J.Biol.Chem. 266:6620-6625
- Erpel, T., P. Hwang, C.S. Craik, R.J. Fletterick, M.E. McGrath 1992. Physical map location of the new Escherichia coli gene eco, encoding the serine protease inhibitor ecotin. J.Bacteriol. 174:1704
- Lee, H.R., J.H. Seol, O.H. Kim, C.S. Lee, S.W. Suh, Y.M. Hong, K. Tanaka, A. Ichihara, D.B. Ha, C.H. Chung 1992. Molecular cloning of the ecotin gene in Escherichia coli. FEBS Lett. 287:53-56
- Eggers, C.T., S.X. Wang, R.J. Fletterick, C.S. Craik 2001. The role of ecotin dimerization in protease inhibition. J.Mol.Biol. 308:975-991
- Eggers, C.T., I.A. Murray, V.A. Delmar, A.G. Day, C.S. Craik 2004. The periplasmic serine protease inhibitor ecotin protects bacteria against neutrophil elastase. Biochem.J. 379:107-118