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Site pyrE
- Name: pyrE
- Type: Gene
- Synonyms
b3642 MG1655 locus tag - Mnemonic: Pyrimidine
- Left End Point: 82.19
- Right End Point: 82.20
- Products:
orotate phosphoribosyltransferase - Direction: <
- Properties:
Property Comment auxotrophy-pur/pyr uracil auxotroph - Priority: 1
- 5 Alleles of This Gene
pyrE41 pyrE60 pyrE69 pyrE70 pyrE748(del)::kan - External Database Links:
Host Site Page Links NCBI/GenBank X00781 EcoGene.org EG10808 EcoliWiki pyrE - Comment:
- References:
- Taylor, A.F., P.G. Siciliano, B. Weiss 1980. Cloning of the dut (deoxyuridine triphosphatase) gene of Escherichia coli. Gene 9:321-336
- Poulsen, P., K.F. Jensen, P. Valentin-Hansen, P. Carlsson, L.G. Lundberg 1983. Nucleotide sequence of the Escherichia coli pyrE gene and of the DNA in front of the protein-coding region. Eur.J.Biochem. 135:223-229
- Poulsen, P., F. Bonekamp, K.F. Jensen 1984. Structure of the Escherichia coli pyrE operon and control of pyrE expression by a UTP modulated intercistronic attenuation. EMBO J. 3:1783-1790
- Poulsen, P., K.F. Jensen 1991. Three genes preceding pyrE on the Escherichia coli chromosome are essential for survival and normal cell morphology in stationary culture and at high temperature. Res.Microbiol. 142:283-288
- Andersen, J.T., P. Poulsen, K.F. Jensen 1992. Attenuation in the rph-pyrE operon of Escherichia coli and processing of the dicistronic mRNA. Eur.J.Biochem. 206:381-390
- Jensen, K.F. 1993. The Escherichia coli K-12 "wild types" W3110 and MG1655 have an rph frameshift mutation that leads to pyrimidine starvation due to low pyrE expression levels. J.Bacteriol. 175:3401-3407