Site secE
- Name: secE
- Type: Gene
- Synonyms
b3981 MG1655 locus tag prlG - Mnemonic: secretory (monitor)
- Left End Point: 89.99
- Right End Point: 90.00
- Products:
preprotein translocase component SecE-G-Y cytoplasmic membrane translocation complex - Direction: >
- Properties:
Property Comment encodes membrane protein NULL transport gene NULL - Priority: 0
- 2 Alleles of This Gene
secE15(Cs) secE501(Cs) - External Database Links:
Host Site Page Links EcoGene.org EG10939 EcoliWiki secE - Comment:
- References:
- Riggs, P.D., A.I. Derman, J.R. Beckwith 1988. A mutation affecting the regulation of a secA-lacZ fusion defines a new sec gene. Genetics 118:571-579
- Schatz, P.J., P.D. Riggs, A. Jacq, M.J. Fath, J.R. Beckwith 1989. The secE gene encodes an integral membrane protein required for protein export in Escherichia coli. Genes Dev. 3:1035-1044
- Stader, J., L.J. Gansheroff, T.J. Silhavy 1989. New suppressors of signal-sequence mutations, prlG, are linked tightly to the secE gene of Escherichia coli. Genes Dev. 3:1045-1052
- Bieker, K.L., T.J. Silhavy 1990. PrlA (SecY) and PrlG (SecE) interact directly and function sequentially during protein translocation in E. coli. Cell 61:833-842
- Matsuyama, S., J. Akimaru, S. Mizushima 1990. SecE-dependent overproduction of SecY in Escherichia coli. Evidence for interaction between two components of the secretory machinery. FEBS Lett. 269:96-100
- Bieker, K.L., G.J. Phillips, T.J. Silhavy 1990. The sec and prl genes of Escherichia coli. J.Bioenerg.Biomembr. 22:291-310
- Downing, W.L., S.L. Sullivan, M.E. Gottesman, P.P. Dennis 1990. Sequence and transcriptional pattern of the essential Escherichia coli secE-nusG operon. J.Bacteriol. 172:1621-1627
- Schatz, P.J., K.L. Bieker, K.M. Ottemann, T.J. Silhavy, J.R. Beckwith 1991. One of three transmembrane stretches is sufficient for the functioning of the SecE protein, a membrane component of the E. coli secretion machinery. EMBO J. 10:1749-1757
- Pugsley, A.P., M.G. Kornacker, I. Poquet 1991. The general protein-export pathway is directly required for extracellular pullulanase secretion in Escherichia coli K12. Mol.Microbiol. 5:343-352
- Akimaru, J., S. Matsuyama, H. Tokuda, S. Mizushima 1991. Reconstitution of a protein translocation system containing purified SecY, SecE, and SecA from Escherichia coli. Proc.Natl.Acad.Sci.USA 88:6545-6549
- Nishiyama, K., S. Mizushima, H. Tokuda 1992. The carboxyl-terminal region of SecE interacts with SecY and is functional in the reconstitution of protein translocation activity in Escherichia coli. J.Biol.Chem. 267:7170-7176
- Sugai, M., H.C. Wu 1992. Export of the outer membrane lipoprotein is defective in secD, secE and secF mutants of Escherichia coli. J.Bacteriol. 174:2511-2516
- Brundage, L., C.J. Fimmel, S. Mizushima, W. Wickner 1992. SecY, SecE and band 1 form the membrane-embedded domain of Escherichia coli preprotein translocase. J.Biol.Chem. 267:4166-4170
- Kosic, N., M. Sugai, C.K. Fan, H.C. Wu 1993. Processing of lipid-modified prolipoprotein requires energy and sec gene products in vivo. J.Bacteriol. 175:6113-6117
- Taura, T., T. Baba, Y. Akiyama, K. Ito 1993. Determinants of the quantity of the stable SecY complex in the Escherichia coli cell. J.Bacteriol. 175:7771-7775
- Blattner, F.R., V.D. Burland, G. Plunkett, H.J. Sofia, D.L. Daniels 1993. Analysis of the Escherichia coli genome. IV. DNA sequence of the region from 89.2 to 92.8 minutes. Nucleic Acids Res. 21:5408-5417
- Pogliano, K.J., J.R. Beckwith 1993. The Cs sec mutants of Escherichia coli reflect the cold sensitivity of protein export itself. Genetics 133:763-773
- Murphy, C.K., J.R. Beckwith 1994. Residues essential for the function of SecE, a membrane component of the Escherichia coli secretion apparatus, are located in a conserved cytoplasmic region. Proc.Natl.Acad.Sci.USA 91:2557-2561
- Joly, J.C., M.R. Leonard, W. Wickner 1994. Subunit dynamics in Escherichia coli preprotein translocase. Proc.Natl.Acad.Sci.USA 91:4703-4707
- Douville, K., M. Leonard, L. Brundage, K. Nishiyama, H. Tokuda, S. Mizushima, W. Wickner 1994. Band 1 subunit of Escherichia coli preprotein translocase and integral membrane export factor P12 are the same protein. J.Biol.Chem. 269:18705-18707
- Baba, T., T. Taura, T. Shimoike, Y. Akiyama, T. Yoshihisa, K. Ito 1994. A cytoplasmic domain is important for the formation of a SecY-SecE translocator complex. Proc.Natl.Acad.Sci.USA 91:4539-4543
- Flower, A.M., R.C. Doebele, T.J. Silhavy 1994. PrlA and PrlG suppressors reduce the requirement for signal sequence recognition. J.Bacteriol. 176:5607-5614
- Murphy, CK, EJ Stewart, J Beckwith 1995. A double counter-selection system for the study of null alleles of essential genes in Escherichia coli. Gene 155(1):1-7.
- Douville, K., A. Price, J. Eichler, A. Economou, W. Wickner 1995. SecYEG and SecA are the stoichiometric components of preprotein translocase. J.Biol.Chem. 270:20106-20111
- Danese, P.N., C.K. Murphy, T.J. Silhavy 1995. Multicopy suppression of cold-sensitive sec mutations in Escherichia coli. J.Bacteriol. 177:4969-4973
- Pohlschroder, M., C. Murphy, J.R. Beckwith 1996. In vivo analyses of interactions between SecE and SecY, core components of the Escherichia coli protein translocation machinery. J.Biol.Chem. 271:19908-19914