Site hslV
- Name: hslV
- Type: Gene
- Synonyms
b3932 MG1655 locus tag htpO - Mnemonic: heat-shock loci
- Left End Point: 88.79
- Right End Point: 88.81
- Products:
proteasome-like HslVU complex, ATP dependent protease - Direction: <
- Properties:
Property Comment encodes a protease NULL - Priority: 0
- 1 Alleles of This Gene
hslV720(del)::kan - External Database Links:
Host Site Page Links EcoGene.org EG11676 EcoliWiki hslV - Comment:
- similar to proteasome beta subunits; requires HslU ATPase for peptide hydrolysis
- References:
- Chuang, S.E., V.D. Burland, G. Plunkett, D.L. Daniels, F.R. Blattner 1993. Sequence analysis of four new heat-shock genes constituting the hslTS/ibpAB and hslVU operons in Escherichia coli. Gene 134:1-6
- Gage, D.J., F.C. Neidhardt 1993. Adaptation of Escherichia coli to the uncoupler of oxidative phosphorylation 2,4-dinitrophenol. J.Bacteriol. 175:7105-7108
- Chuang, S.E., F.R. Blattner 1993. Characterization of twenty-six new heat shock genes of Escherichia coli. J.Bacteriol. 175:5242-5252
- Yoo, S.J., J.H. Seol, D.H. Shin, M. Rohrwild, M.S. Kang, K. Tanaka, A.L. Goldberg, C.H. Chung 1996. Purification and characterization of the heat shock proteins HslV and HslU that form a new ATP-dependent protease in Escherichia coli. J.Biol.Chem. 271:
- Yoo, S.J., J.H. Seol, M.S. Kang, C.H. Chung 1996. Poly-L-lysine activates both peptide and ATP hydrolysis by the ATP-dependent HslVU protease in Escherichia coli. Biochem.Biophys.Res.Commun. 229:531-535
- Missiakas, D., F. Schwager, J.M. Betton, C. Georgopoulos, S. Raina 1996. Identification and characterization of HslV HslU (ClpQ ClpY) proteins involved in overall proteolysis of misfolded proteins in Escherichia coli. EMBO J. 15:6899-6909
- Rohrwild, M., O. Coux, H.C. Huang, R.P. Moerschell, S.J. Yoo, J.H. Seol, C.H. Chung, A.L. Goldberg 1996. HslV-HslU: A novel ATP-dependent protease complex in Escherichia coli related to the eukaryotic proteasome. Proc.Natl.Acad.Sci.USA 93:5808-5813
- Khattar, M.M. 1997. Overexpression of the hslVU operon suppresses SOS-mediated inhibition of cell division in Escherichia coli. FEBS Lett. 414:402-404
- Kanemori, M., K. Nishihara, H. Yanagi, T. Yura 1997. Synergistic roles of HslVU and other ATP-dependent proteases in controlling in vivo turnover of sigma32 and abnormal proteins in Escherichia coli. J.Bacteriol. 179:7219-7225