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Site cpxR
- Name: cpxR
- Type: Gene
- Synonyms
b3912 MG1655 locus tag - Mnemonic: conjugative plasmid eXpression
- Left End Point: 88.43
- Right End Point: 88.45
- Products:
regulator in two-component CpxAR system - Direction: <
- Priority: 0
- 2 Alleles of This Gene
cpxR772(del)::kan cpxR791-YFP(::cat) - External Database Links:
Host Site Page Links EcoGene.org EG10020 EcoliWiki cpxR - Comment:
- cognate regulator for the membrane sensor, CpxA in a 2-component signal transduction system. Pleiotropic effects (see cpxA comments);surface sensing, adhesion signalling; NlpE-induced.affects biofilm.
- References:
- Dong, J., S. Iuchi, H.S. Kwan, Z. Lu, E.C.C. Lin 1993. The deduced amino-acid sequence of the cloned cpxR gene suggests the protein is the cognate regulator for the membrane sensor, CpxA, in a two-component signal transduction system of Escherichia col
- Cosma, C.L., P.N. Danese, J.H. Carlson, T.J. Silhavy, W.B. Snyder 1995. Mutational activation of the Cpx signal transduction pathway of Escherichia coli suppresses the toxicity conferred by certain envelope-associated stresses. Mol.Microbiol. 18:491-50
- Raivio, T., T.J. Silhavy 1997. Transduction of envelope stress in Escherichia coli by the Cpx two-component system. J.Bacteriol. 179:7724-7733