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Site fkpA

• Name: fkpA
• Type: Gene
  Synonyms

  b3347	MG1655 locus tag

  
  
• Mnemonic: FK506-binding protein
• Left End Point: 74.89
• Right End Point: 74.91
  Products:

  FKBP, Mip-like protein, periplasmic

  
  
• Direction: <
• Properties:

  Property	Comment
  member of	PPI sequence family

  
  
• Priority: 0
  2 Alleles of This Gene

  fkpA754(del)::kan

  fkpA791-YFP(::cat)

  
  
• External Database Links:

  Host Site	Page Links
  EcoGene.org	EG12900
  EcoliWiki	fkpA

  
  
• Comment:
  • Proposed role as folding catalysts or chaperones in extracytopl.compartments.Homology to macrolide FK506 binding proteins,which are PPI's.Required for PhiX174 lysis. Muts incr.sigmaE regulon activity
• References:
  • Horne, S.M., K.D. Young 1995. Escherichia coli and other species of the Enterobacteriaceae encode a protein similar to the family of Mip-like FK506-binding proteins. Arch.Microbiol. 163:357-365
  
  
  • Missiakas, D., J.M. Betton, S. Raina 1996. New components of protein folding in extracytoplasmic compartments of Escherichia coli SurA, FkpA and Skp/OmpH. Mol.Microbiol. 21:871-884