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Site gadC
- Name: gadC
- Type: Gene
- Synonyms
b1492 MG1655 locus tag xas original discoverers, 1995, who suggested change, 1996 ref.below. - Mnemonic: glutamate deCase
- Left End Point: 33.78
- Right End Point: 33.81
- Products:
GABA-glutamate antiporter - Direction: <
- Priority: 0
- 1 Alleles of This Gene
gadC785(del)::kan - External Database Links:
Host Site Page Links EcoGene.org EG12456 EcoliWiki gadC - Comment:
- Glutamate deCase alkalinization cycle protects coli from cytoplasmic acidification. Transcribed with gadB, regulated by acid, salt, and stationary phase, involving GadX, H-NS, and RpoS.
- References:
- Hersh, B.M., F.T. Farooq, D.N. Barstad, D.L. Blankenhorn, J.L. Slonczewski 1996. A glutamate-dependent acid resistance gene in Escherichia coli. J.Bacteriol. 178:3978-3981
- De Biase, D., A. Tramonti, F. Bossa, P. Visca 1999. The response to stationary-phase stress conditions in Escherichia coli: role and regulation of the glutamic acid decarboxylase system. Mol.Microbiol. 32:1198-1211
- Tramonti, A., P. Visca, M. De Canio, M. Falconi, D. De Biase 2002. Functional characterization and regulation of gadX, a gene encoding an AraC/XylS-like transcriptional activator of the Escherichia coli glutamic acid decarboxylase system. J.Bacteriol.