E. coli Genetic Resources at Yale
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Site trmU

• Name: trmU
• Type: Gene
  Synonyms

  asuE	antisuppressor
  b1133	MG1655 locus tag
  mnmA
  ycfC	Blattner et al. seq.

  
  
• Mnemonic: tRNA methyltransferase
• Left End Point: 25.69
• Right End Point: 25.72
  Products:

  tRNA-modifying enzyme; 2-thiouridine synthesis

  
  
• Direction: <
• Priority: 0
  2 Alleles of This Gene

  trmU721(del)::kan

  trmU793-YFP(::cat)

  
  
• External Database Links:

  Host Site	Page Links
  EcoGene.org	EG11344
  EcoliWiki	trmU

  
  
• Comment:
  • Because of the conflict between asu for asparagine utilization and asuA-F for antisuppressors, Soll et al. have agreed to use trmU for name of this locus
• References:
  • Sullivan, M.A., J.F. Cannon, F.H. Webb, A. Bock 1985. Antisuppressor mutation in Escherichia coli defective in biosynthesis of 5-methylaminomethyl-2-thiouridine. J.Bacteriol. 161:368-376
  
  
  • Rogers, K.C., A.T. Crescenzo, D. Soll 1995. Aminoacylation of transfer RNAs with 2-thiouridine derivatives in the wobble position of the anticodon. Biochimie 77:66-74
  
  
  • Green, S.M., T. Malik, I.G. Giles, W.T. Drabble 1996. The purB gene of Escherichia coli K-12 is located in an operon. Microbiology 142:3219-3230