Site pheA
- Name: pheA
- Type: Gene
- Synonyms
b2599 MG1655 locus tag - Mnemonic: Phenylalanine
- Left End Point: 58.97
- Right End Point: 59.00
- Products:
chorismate mutase-prephenate dehydratase - Direction: >
- Properties:
Property Comment auxotrophy-amino acid NULL - Priority: 0
- 8 Alleles of This Gene
pheA18::Tn10 pheA2::Mu pheA3141::Tn10kan pheA3::Mu pheA7 pheA762(del)::kan pheA905 pheA97 - External Database Links:
Host Site Page Links NCBI/GenBank M10431 NCBI/GenBank X02137 EcoGene.org EG10707 EcoliWiki pheA - Comment:
- Selectable phenotype. Constitutive: fluorophenylalanine resistance.
- References:
- Gowrishankar, J., J. Pittard 1982. Regulation of phenylalanine biosynthesis in Escherichia coli K-12: control of transcription of the pheA operon. J.Bacteriol. 150:1130-1137
- Gowrishankar, J., J. Pittard 1982. Construction from Mu d1 (lac Ap^r) lysogens of lambda bacteriophage bearing promoter-lac fusions: isolation of lambda ppheA-lac. J.Bacteriol. 150:1122-1129
- Hudson, G.S., B.E. Davidson 1984. Nucleotide sequence and transcription of the phenylalanine and tyrosine operons of Escherichia coli K-12. J.Mol.Biol. 180:1023-1051
- Gavini, N., B.E. Davidson 1990. pheAo mutants of Escherichia coli have a defective pheA attenuator. J.Biol.Chem. 265:21532-21535
- Gavini, N., B.E. Davidson 1991. Regulation of pheA expression by the pheR product in Escherichia coli is mediated through attenuation of transcription. J.Biol.Chem. 266:7750-7753
- Gavini, N., L. Pulakat 1991. Role of ribosome release in the basal level of expression of the Escherichia coli gene pheA. J.Gen.Microbiol. 137:679-684
- Zhang, S.., G. Pohnert, P. Kongsaeree, D.B. Wilson, J. Clardy, B. Ganem 1998. Chorismate mutase-prephenate dehydratase from Escherichia coli.Study of catalytic and regulatory domains using genetically engineered proteins. J.Biol.Chem. 273:6248-6253