Site ftsK
- Name: ftsK
- Type: Gene
- Synonyms
b0890 MG1655 locus tag dinH Lewis et al. - Mnemonic: filamentation temperature sensitivity
- Left End Point: 20.10
- Right End Point: 20.18
- Products:
FtsK septum formation protein - Direction: >
- Properties:
Property Comment affects cell division/growth late stage of division, not chrs.replic or segreg. encodes membrane protein NULL encodes NA-binding protein has domain with nucleotide-binding consensus - Priority: 0
- 2 Alleles of This Gene
ftsK793-YFP(::cat) ftsK794-YFP(::cat) - External Database Links:
Host Site Page Links NCBI/GenBank Z49932 EcoGene.org EG13226 EcoliWiki ftsK - Comment:
- homology with SpoIIIE, subtilis gene involved in chromosome transfer to spore; involved in septation; mutant phenotype suppressed by deletion of dacA. Encodes septal protein.
- References:
- Lewis, L.K., M.E. Jenkins, D.W. Mount 1992. Isolation of DNA damage-inducible promoters in Escherichia coli: regulation of polB (dinA), dinG, and dinH by LexA repressor. J.Bacteriol. 174:3377-3385
- Begg, K.J., S.J. Dewar, W.D. Donachie 1995. A new Escherichia coli cell division gene, ftsK. J.Bacteriol. 177:6211-6222
- Diez, A.A., A. Farewell, U. Nannmark, T. Nystrom 1997. A mutation in the ftsK gene of Escherichia coli affects cell-cell separation, stationary-phase survival, stress adaptation, and expression of the gene encoding the stress protein UspA. J.Bacteriol.
- Yu, X.C., A.H. Tran, Q. Sun, W. Margolin 1998. Localization of cell division protein FtsK to the Escherichia coli septum and identification of a potential N-terminal targeting domain. J.Bacteriol. 180:1296-1304
- Gustavsson, N., A. Diez, T. Nystrom 2002. The universal stress protein paralogues of Escherichia coli are co-ordinately regulated and co-operate in the defence against DNA damage. Mol.Microbiol. 43:107-117
- Hale, C.A., P.A. de Boer 2002. ZipA is required for recruitment of FtsK, FtsQ, FtsL, and FtsN to the septal ring in Escherichia coli. J.Bacteriol. 184:2552-2556
- Grenga, L, G Luzi, L Paolozzi, P Ghelardini 2008. The Escherichia coli FtsK functional domains involved in its interaction with its divisome protein partners. FEMS Microbiol. Lett. 287(2):163-7.