Site mutS
- Name: mutS
- Type: Gene
- Synonyms
b2733 MG1655 locus tag fdv formate dehydrogenase activity - Mnemonic: Mutator
- Left End Point: 61.54
- Right End Point: 61.60
- Products:
mismatch repair protein - Direction: >
- Properties:
Property Comment repair system gene mediates methyl-directed mismatch repair - Priority: 1
- 6 Alleles of This Gene
mutS104::mini-Tn10 mutS201::Tn5 mutS210 mutS215::Tn10 mutS3 mutS738(del)::kan - External Database Links:
Host Site Page Links NCBI/GenBank M64730 FlyBase FBgn0015546 EcoGene.org EG10625 EcoliWiki mutS - Comment:
- Selectable phenotype. Streptomycin resistance; azaserine resistance; chemostat growth.
- References:
- Siegel, E., V. Bryson 1967. Mutator gene of Escherichia coli. J.Bacteriol. 94:38-47
- Helling, R.B. 1968. Selection of a mutant of Escherichia coli which has high mutation rates. J.Bacteriol. 96:975-980
- Cox, E.C., T. Gibson 1974. Selection for high mutation rates in chemostats. Genetics 77:169-184
- Sankar, P., J.H. Lee, K.T. Shanmugam 1988. Gene-product relationships of fhlA and fdv genes of Escherichia coli. J.Bacteriol. 170:5440-5445
- Schlensog, V., A. Bock 1991. The Escherichia coli fdv gene probably encodes mutS and is located at minute 58.8 adjacent to the hyc-hyp gene cluster. J.Bacteriol. 173:7414-7415
- Wu, T.-H., M.G. Marinus 1994. Dominant negative mutator mutations in the mutS gene of Escherichia coli. J.Bacteriol. 176:5393-5400
- Feng, G., M.E. Winkler 1995. Single-step purifications of His6-MutH, His6-MutL and His6-MutS repair proteins of Escherichia coli K-12. Biotechniques 19:956-965
- Rasmussen, L.J., L. Samson 1996. The Escherichia coli MutS DNA mismatch binding protein specifically binds O(6)-methylguanine DNA lesions. Carcinogenesis 17:2085-2088
- Tsui, H.C., G. Feng, M.E. Winkler 1997. Negative regulation of mutS and mutH repair gene expression by the Hfq and RpoS global regulators of Escherichia coli K-12. J.Bacteriol. 179:7476-7487
- Liu, S.K., J.N. Tseng, D. Shiuan, P.C. Hanawalt 1997. Preferential mutagenesis of lacZ integrated at unique sites in the Escherichia coli chromosome. Mol.Gen.Genet. 255:449-459