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Site mutH
- Name: mutH
- Type: Gene
- Synonyms
b2831 MG1655 locus tag mutR prv - Mnemonic: Mutator
- Left End Point: 63.97
- Right End Point: 63.98
- Products:
repair protein, homology with Sau3AI and PvuII - Direction: <
- Properties:
Property Comment repair system gene mediates methyl-directed mismatch repair - Priority: 1
- 5 Alleles of This Gene
mutH34 mutH471::kan mutH472::mini-Tn10 mutH756(del)::kan mutH791-YFP(::cat) - External Database Links:
Host Site Page Links NCBI/GenBank Y00113 EcoGene.org EG10624 EcoliWiki mutH - Comment:
- Selectable phenotype. Streptomycin resistance; azaserine resistance; chemostat growth.
- References:
- Siegel, E., V. Bryson 1967. Mutator gene of Escherichia coli. J.Bacteriol. 94:38-47
- Helling, R.B. 1968. Selection of a mutant of Escherichia coli which has high mutation rates. J.Bacteriol. 96:975-980
- Cox, E.C., T. Gibson 1974. Selection for high mutation rates in chemostats. Genetics 77:169-184
- Graftstrom, R.H., R.H. Hoess 1983. Cloning of mutH and identification of the gene product. Gene 22:245-253
- Graftstrom, R.H., R.H. Hoess 1987. Nucleotide sequence of the Escherichia coli mutH gene. Nucleic Acids Res. 15:3073-3083
- Wright, F. 1990. Nucleotide sequence of the mutH gene of Escherichia coli K12 and comparison with that of Salmonella typhimurium?????. Gene 87:15021
- Feng, G., M.E. Winkler 1995. Single-step purifications of His6-MutH, His6-MutL and His6-MutS repair proteins of Escherichia coli K-12. Biotechniques 19:956-965
- Tsui, H.C., G. Feng, M.E. Winkler 1997. Negative regulation of mutS and mutH repair gene expression by the Hfq and RpoS global regulators of Escherichia coli K-12. J.Bacteriol. 179:7476-7487