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Site recD
- Name: recD
- Type: Gene
- Synonyms
b2819 MG1655 locus tag hopE Niki et al. - Mnemonic: Recombination
- Left End Point: 63.56
- Right End Point: 63.60
- Products:
exonuclease V alpha subunit RecBCD enzyme subunit exonuclease V subunit exonuclease/helicase - Direction: <
- Priority: 1
- 7 Alleles of This Gene
recD1009(Nuc-) recD1014(Nuc-) recD1901::Tn10 recD1903::Tn10d(Tet) recD1911(del)::dhfr recD744(del)::kan recD792-YFP(::cat) - External Database Links:
Host Site Page Links NCBI/GenBank X04582 EcoGene.org EG10826 EcoliWiki recD - Comment:
- Recomb.and DNA repair.Muts are recomb.proficient,in some cases hyper-Rec,resistant to DNA damage and viable,lack ss and dsDNA exonuc.activities.No restriction.RecBCD req.for MMS repair not recomb.
- References:
- Amundsen, S.K., A.F. Taylor, A.M. Chaudhury, G.R. Smith 1986. recD: the gene for an essential third subunit of exonuclease V. Proc.Natl.Acad.Sci.USA 83:5558-5562
- Finch, P.W., A. Storey, K. Brown, I.D. Hickson, P.T. Emmerson 1986. Complete nucleotide sequence of recD, the structural gene for the alpha subunit of exonuclease V of Escherichia coli. Nucleic Acids Res. 14:8583-8594
- Biek, D.P., S.N. Cohen 1986. Identification and characterization of recD, a gene affecting plasmid maintenance and recombination in Escherichia coli. J.Bacteriol. 167:594-603
- Niki, H., T. Ogura, S. Hiraga 1990. Linear multimer formation of plasmid DNA in Escherichia coli hopE (recD) mutants. Mol.Gen.Genet. 224:1-9
- Clark, A.J. 1991. rec genes and homologous recombination proteins in Escherichia coli. Biochimie 73:523-532
- Taylor, A.F., G.R. Smith 1995. Strand specificity of nicking of DNA at Chi sites by RecBCD enzyme. Modulation by ATP and magnesium levels. J.Biol.Chem. 270:24459-24467
- Taylor, A.F., G.R. Smith 1995. Monomeric RecBCD enzyme binds and unwinds DNA. J.Biol.Chem. 270:24451-24458