Site melB
- Name: melB
- Type: Gene
- Synonyms
b4120 MG1655 locus tag mel-4 - Mnemonic: Melibiose
- Left End Point: 93.57
- Right End Point: 93.60
- Products:
thiomethylgalactoside permease II melibiose permease - Direction: >
- Priority: 1
- 2 Alleles of This Gene
melB4 melB746(del)::kan - External Database Links:
Host Site Page Links NCBI/GenBank K01991 EcoGene.org EG10578 EcoliWiki melB - Comment:
- Selectable phenotype. Regulatory, in lacI: growth on raffinose. Regulatory, loss of catabolite repression: growth on melibiose + a-methylglucoside.
- References:
- Lester, B., D.M. Bonner 1957. Genetic control of raffinose utilization in Escherichia coli. J.Bacteriol. 73:544-552
- Hanatani, M., H. Yazyu, S. Shiota-Niiya, Y. Moriya, H. Kanazawa, M. Futai, T. Tsuchiya 1984. Physical and genetic characterization of the melibiose operon and identification of the gene products in Escherichia coli. J.Biol.Chem. 259:1807-1812
- Yazyu, H., S. Shiota-Niiya, T. Shimamoto, H. Kanazawa, M. Futai, T. Tsuchiya 1984. Nucleotide sequence of the melB gene and characteristics of deduced amino acid sequence of the melibiose carrier in Escherichia coli. J.Biol.Chem. 259:4320-4326
- Keen, J., J. Williams, S.J. Busby 1996. Location of essential sequence elements at the Escherichia coli melAB promoter. Biochem.J. 318:443-449
- Bassilana, M., C. Gwizdek 1996. In vivo membrane assembly of the E.coli polytopic protein, melibiose permease, occurs via a Sec-independent process which requires the protonmotive force. EMBO J. 15:5202-5208
- Ding, P.Z., T.H. Wilson 2001. The effect of modifications of the charged residues in the transmembrane helices on the transport activity of the melibiose carrier of Escherichia coli. Biochem.Biophys.Res.Commun. 285:348-354