Site nei
- Name: nei
- Type: Gene
- Synonyms
b0714 MG1655 locus tag - Mnemonic: endonuclease eight
- Left End Point: 16.06
- Right End Point: 16.08
- Products:
endonuclease VIII DNA glycosylase/apurinic lyase, deoxyinosine-specific - Direction: >
- Priority: 0
- 2 Alleles of This Gene
nei-764(del)::kan nei-791-YFP(::cat) - External Database Links:
Host Site Page Links EcoGene.org EG13237 EcoliWiki nei - Comment:
- References:
- Melamede, R.J., Z. Hatahet, Y.W. Kow, H. Ide, S.S. Wallace 1994. Isolation and characterization of endonuclease VIII from Escherichia coli. Biochemistry 33:1255-1264
- Jiang, D., Z. Hatahet, J.O. Blaisdell, R.J. Melamede, S.S. Wallace 1997. Escherichia coli endonuclease VIII: cloning, sequencing, and overexpression of the nei structural gene and characterization of nei and nei nth mutants. J.Bacteriol. 179:3773-3782
- Saito, Y., F. Uraki, S. Nakajima, A. Asaeda, K. Ono, K. Kubo, K. Yamamoto 1997. Characterization of endonuclease III (nth) and endonuclease VIII (nei) mutants of Escherichia coli K-12. J.Bacteriol. 179:3783-3785
- Jiang, D., Z. Hatahet, R.J. Melamede, Y.W. Kow, S.S. Wallace 1997. Characterization of Escherichia coli endonuclease VIII. J.Biol.Chem. 272:32230-32239
- Harrison, L., Z. Hatahet, A.A. Purmal, S.S. Wallace 1998. Multiply damaged sites in DNA: interactions with Escherichia coli endonucleases III and VIII. Nucleic Acids Res. 26:932-941
- Tano, K., Y. Iwamatsu, S. Yasuhira, H. Utsumi, K. Takimoto 2001. Increased base change mutations at G:C pairs in Escherichia coli deficient in endonuclease III and VIII. Journal of Radiation Research 42:409-413
- Zharkov, D.O., G. Golan, R. Gilboa, A.S. Fernandes, S.E. Gerchman, J.H. Kycia, R.A. Rieger, A.P. Grollman, G. Shoham 2002. Structural analysis of an Escherichia coli endonuclease VIII covalent reaction intermediate. EMBO J. 21:789-800