E. coli Genetic Resources at Yale
CGSC, The Coli Genetic Stock Center

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Site lpp

• Name: lpp
• Type: Gene
  Synonyms

  b1677	MG1655 locus tag
  mlpA

  
  
• Mnemonic: Lipoprotein
• Left End Point: 37.84
• Right End Point: 37.84
  Products:

  murein lipoprotein

  Braun's lipoprotein

  prolipoprotein

  
  
• Direction: >
• Priority: 1
  8 Alleles of This Gene

  lpp-1

  lpp-2

  lpp-21

  lpp-254(del)

  lpp-3

  lpp-5508

  lpp-6

  lpp-752(del)::kan

  
  
• External Database Links:

  Host Site	Page Links
  NCBI/GenBank	J01645
  EcoGene.org	EG10544
  EcoliWiki	lpp

  
  
• Comment:
  • Selectable phenotype. Loss: globomycin resistance.
• References:
  • Braun, V., V. Bosch 1972. Sequence of the murein-lipoprotein and the attachment site of the lipid. Eur.J.Biochem. 28:51-69
  
  
  • Rotering, H., V. Braun 1977. Lipid deficiency in a lipoprotein mutant of Escherichia coli. FEBS Lett. 83:41-44
  
  
  • Smith, B.R., R. Schleif 1978. Nucleotide sequence of the L-arabinose regulatory region of Escherichia coli K12. J.Biol.Chem. 253:6931-6933
  
  
  • Nakamura, K., M. Inouye 1979. DNA sequence of the gene for the outer membrane lipoprotein of E. coli: an extremely AT-rich promoter. Cell 18:1109-1117
  
  
  • Nakamura, K., R.M. Pirtle, I.L. Pirtle, K. Takeishi, M. Inouye 1980. Messenger ribonucleic acid of the lipoprotein of the Escherichia coli outer membrane.II.The complete nucleotide sequence. J.Biol.Chem. 255:210-216
  
  
  • Zwiebel, L., M. Inukai, K. Nakamura, M. Inouye 1981. Preferential selection of deletion mutations of the outer membrane lipoprotein gene of Escherichia coli by globomycin. J.Bacteriol. 145:654-656
  
  
  • Wu, H.C., J.S. Lai, S. Hayashi, C.Z. Giam 1982. Biogenesis of membrane lipoproteins in Escherichia coli. Biophys J 37:307-315
  
  
  • Grogan, D.W., J.E. Cronan 1984. Genetic characterization of Escherichia coli cyclopropane fatty acid (cfa) locus and neighboring loci. Mol.Gen.Genet. 196:367-372
  
  
  • Giam, C.Z., S. Hayashi, H.C. Wu 1984. Characterization of a novel lipoprotein mutant in Escherichia coli. J.Biol.Chem. 259:5601-5605
  
  
  • Hayashi, S., S.-Y. Chang, S. Chang, C.Z. Giam, H.C. Wu 1985. Modification and processing of internalized signal sequences of prolipoprotein in Escherichia coli and in Bacillus subtilis. J.Biol.Chem. 260:5753-5759
  
  
  • Tian, G., H.C. Wu, P.H. Ray, P.C. Tai 1989. Temperature-dependent insertion of prolipoprotein into Escherichia coli membrane vesicles and requirements for ATP, soluble factors, and functional SecY protein for the overall translocation process. J.Bacter
  
  
  • Yakushi, T., T. Tajima, S. Matsuyama, H. Tokuda 1997. Lethality of the covalent linkage between mislocalized major outer membrane lipoprotein and the peptidoglycan of Escherichia coli. J.Bacteriol. 179:2857-2862
  
  
  • Germon, P., M.C. Ray, A. Vianney, J.C. Lazzaroni 2001. Energy-dependent conformational change in the TolA protein of Escherichia coli involves its N-terminal domain, TolQ, and TolR. J.Bacteriol. 183:4110-4114