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Site lpcA
- Name: lpcA
- Type: Gene
- Synonyms
b0222 MG1655 locus tag gmhA Valvano tfr tfrA yafI - Mnemonic: Lipopolysaccharide core
- Left End Point: 5.35
- Right End Point: 5.39
- Products:
phosphoheptose isomerase - Direction: >
- Priority: 1
- 4 Alleles of This Gene
lpcA1 lpcA2 lpcA740(del)::kan lpcA8 - External Database Links:
Host Site Page Links EcoGene.org EG13146 EcoliWiki lpcA - Comment:
- Selectable phenotype. Phage T3 + phage T4 + phage T7 resistance. Sequencing shows it is NOT between pepD and gpt (Heinrich et al., below)
- References:
- VanAlphen, W., B. Lugtenberg, W. Berendsen 1976. Heptose-deficient mutants of Escherichia coli K12 deficient in up to three major outer membrane proteins. Mol.Gen.Genet. 147:263-269
- Henrich, B., U. Schroeder, R. Frank, R. Plapp 1989. Accurate mapping of the Escherichia coli pepD gene by sequence analysis of its 5' flanking region. Mol.Gen.Genet. 215:369-373
- Brooke, J.S., M.A. Valvano 1996. Biosynthesis of inner core lipopolysaccharide in enteric bacteria: identification and characterization of a conserved phosphoheptose isomerase. J.Biol.Chem. 271:3608-3614
- Kneidinger, B., C. Marolda, M. Graninger, A. Zamyatina, F. McArthur, P. Kosma, M.A. Valvano, P. Messner 2002. Biosynthesis pathway of ADP-L-glycero-beta-D-manno-heptose in Escherichia coli. J.Bacteriol. 184:363-369