Site lacZ
- Name: lacZ
- Type: Gene
- Synonyms
b0344 MG1655 locus tag - Mnemonic: Lactose
- Left End Point: 7.81
- Right End Point: 7.88
- Products:
beta-D-galactosidase - Direction: <
- Priority: 1
- External Database Links:
Host Site Page Links EcoGene.org EG10527 EcoliWiki lacZ - Comment:
- Selectable phenotype. Duplication: growth in lactose-limited chemostat. Loss: phenyl- or phenethyl- or orthonitrophenyl galactoside resistance; indicator plate. Change, dup.: growth on lactobio.acid
- References:
- Horiuchi, T., S. Horiuchi, A. Novick 1963. The genetic basis of hyper-synthesis of beta-galactoside. Genetics 48:157-169
- Messer, W., W. Vielmetter 1965. High resolution colony staining for the detection of bacterial growth requirement mutants using naphthol azodye techniques. Biochem.Biophys.Res.Commun. 21:182-186
- Langridge, J. 1969. Mutations conferring quantitative and qualitative increases in beta-galactosidase activity in Escherichia coli. Mol.Gen.Genet. 105:74-83
- Johnston, M.A., H. Pivnick 1970. Use of autocytotoxic beta-D-galactosides for selective growth of Salmonella typhimurium in the presence of coliforms. J.Microbiol.Serol. 16:83-89
- Martinez, D., F. Whitehouse 1973. Selective autocytotoxicity in a model system of Escherichia coli recombinants. J.Bacteriol. 114:882-884
- Hadley, R.G., M. Hu, M. Timmons, K. Yun, R. Deonier 1983. A partial restriction map of the proA-purE region of the E. coli K-12 chromosome. Gene 22:281-287
- Kalnins, A., K. Otto, U. Ruther, B. Muller-Hill 1983. Sequence of the lacZ gene of Escherichia coli. EMBO J. 2:593-597
- Wagner, L.A., R.F. Gesteland, T.J. Dayhuff, R.B. Weiss 1994. An efficient Shine-Delgarno sequence but not translation is necessary for lacZ mRNA stability in Escherichia coli. J.Bacteriol. 176:1683-1688