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Site tufA
- Name: tufA
- Type: Gene
- Synonyms
b3339 MG1655 locus tag kirT kirromycin resistant alleles pulT pulvomycin resistant alleles - Mnemonic: Tu (Elongation) factor, EF-Tu
- Left End Point: 74.75
- Right End Point: 74.78
- Products:
EF-Tu subunit elongation factor-T(translation)u(unstable) - Direction: <
- Properties:
Property Comment kirromycin,pulvomycinR alleles NULL duplicate gene see tufB - Priority: 1
- 3 Alleles of This Gene
tufA1 tufA749(del)::kan tufA791-YFP(::cat) - External Database Links:
Host Site Page Links EcoGene.org EG11036 EcoliWiki tufA - Comment:
- Selectable phenotype. Kirromycin resistance.
- References:
- Van de Klundert, J.A., P.H. Van der Meide, P. Van de Putte, L. Bosch 1978. Mutants of Escherichia coli altered in both genes coding for the elongation factor Tu. Proc.Natl.Acad.Sci.USA 75:4470-4473
- Yokota, T., H. Sugisaki, M. Takanami, Y. Kaziro 1980. The nucleotide sequence of the cloned tufA gene of Escherichia coli. Gene 12:25-31
- Laursen, R.A., J.J. L'Italien, S. Nagarkatti, D.L. Miller 1981. The amino acid sequence of elongation factor Tu of Escherichia coli.The complete sequence. J.Biol.Chem. 256:8102-8109
- Van der Meide, P.H., E. Vijgenboom, M. Dicke, L. Bosch 1982. Regulation of the expression of tufA and tufB, the two genes coding for elongation factor EF-Tu in Escherichia coli. FEBS Lett. 139:325-330
- Zengel, J.M., L. Lindahl 1982. A secondary promoter for elongation factor Tu synthesis in the str ribosomal protein operon of Escherichia coli. Mol.Gen.Genet. 185:487-492
- An, G., J.S. Lee, J.D. Friesen 1982. Evidence for an internal promoter preceding tufA in the str operon of Escherichia coli. J.Bacteriol. 149:548-553
- Kushiro, M., M. Shimizu, K. Tomita 1987. Molecular cloning and sequence determination of the tuf gene coding for the elongation factor Tu of Thermus thermophilus HB8. Eur.J.Biochem. 170:93-98
- Kraal, B., L.A. Zeef, J.R. Mesters, K. Boon, E.L. Vorstenbosch, L. Bosch, P.H. Anborgh, A. Parmeggiani, R. Hilgenfeld 1995. Antibiotic resistance mechanisms of mutant EF-Tu species in Escherichia coli. Biochem.Cell Biol. 73:1167-1177
- Wiborg, O., C. Andersen, C.R. Knudsen, B.F.C. Clark, J. Nyborg 1996. Mapping Escherichia coli elongation factor Tu residues involved in binding of aminoacyl-tRNA. J.Biol.Chem. 271:20406-20411
- Talens, A., K. Boon, B. Kraal, L. Bosch 1996. Translational activities of EF-Tu [G222D] which cannot be reconciled with the classical scheme of the polypeptide chain elongation cycle. Biochem.Biophys.Res.Commun. 225:961-967
- Guillon, J.M., S. Heiss, J. Soutourina, Y. Mechulam, S. Laalami, M. Grunberg-Manago, S. Blanquet 1996. Interplay of methionine tRNAs with translation elongation factor Tu and translation initiation factor 2 in Escherichia coli. J.Biol.Chem. 271:22321-2